N-cyclohexyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-amine

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Chemical Name:N-cyclohexyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-amine
CAS No.:1315494-99-5
Molecular Formula:C₁₉H₂₀N₄O₄S
Molecular Weight:400.458
Hs Code.:

Synonyms:N-cyclohexyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-cyclohexyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-amine

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Technology Process of N-cyclohexyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-amine

There total 1 articles about N-cyclohexyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1245649-52-8
1-(benzenesulfonyl)-4-chloro-5-nitro-1H-pyrrolo[2,3-b]pyridine

: 108-91-8,157973-60-9
cyclohexylamine

: 1315494-99-5
N-cyclohexyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-amine

Guidance literature:: In isopropyl alcohol; for 1.5h; Inert atmosphere; Reflux;
DOI:10.1021/acsmedchemlett.0c00323

Reference yield: 94.0%

: 1315494-99-5
N-cyclohexyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-amine

: 1315495-00-1
N⁴-cyclohexyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-4,5-diamine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; for 13h; Heating;
DOI:10.1021/acsmedchemlett.0c00323

Reference yield:

: 1315494-99-5
N-cyclohexyl-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-amine

: (5-(1-cyclohexyl-6-(phenylsulfonyl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: palladium 10% on activated carbon; hydrogen / 13 h / Heating

2.1: N,N-dimethyl-formamide; water / 0.17 h / 20 °C

2.2: 1 h / 20 °C

With palladium 10% on activated carbon; hydrogen; In water; N,N-dimethyl-formamide;
DOI:10.1021/acsmedchemlett.0c00323