C₂₄H₃₃N₃O₈

Base Information

• Chemical Name: C₂₄H₃₃N₃O₈
• CAS No.: 1422363-50-5
• Molecular Formula: C₂₄H₃₃N₃O₈
• Molecular Weight: 491.541
• Mol file: 1422363-50-5.mol

Synonyms:C₂₄H₃₃N₃O₈

Chemical Property of C₂₄H₃₃N₃O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₃₃N₃O₈

There total 7 articles about C₂₄H₃₃N₃O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

tert-Butyl N-hydroxycarbamate (36016-38-3) + C19H23BrN2O5 (1422363-49-2) → C24H33N3O8 (1422363-50-5)

Guidance literature:

tert-Butyl N-hydroxycarbamate; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; Cooling with ice;

C₁₉H₂₃BrN₂O₅; In tetrahydrofuran; mineral oil; at 0 ℃; for 4h;

DOI:10.1039/c2cc38382a

Reference yield:

C16H25NO6 (1422363-58-3) → C24H33N3O8 (1422363-50-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: trifluoroacetic acid / dichloromethane / 20 °C

2.1: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline / dichloromethane / 20 °C / Inert atmosphere

3.1: phosphorus tribromide / tetrahydrofuran / 2 h / 0 °C

4.1: sodium hydride / tetrahydrofuran; mineral oil / 20 °C / Cooling with ice

4.2: 4 h / 0 °C

With phosphorus tribromide; sodium hydride; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; mineral oil;

DOI:10.1039/c2cc38382a

Reference yield:

N-allyloxycarbonyl α-allyl-L-glutamate (91871-28-2) → C24H33N3O8 (1422363-50-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline / dichloromethane / 20 °C / Inert atmosphere

2.1: phosphorus tribromide / tetrahydrofuran / 2 h / 0 °C

3.1: sodium hydride / tetrahydrofuran; mineral oil / 20 °C / Cooling with ice

3.2: 4 h / 0 °C

With phosphorus tribromide; sodium hydride; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In tetrahydrofuran; dichloromethane; mineral oil;

DOI:10.1039/c2cc38382a

upstream raw materials:

C₁₆H₂₅NO₆

N-allyloxycarbonyl α-allyl-L-glutamate

Fmoc-Glu(OtBu)-OH

allyl (S)-2-((allyloxycarbonyl)amino)-5-((4-(hydroxymethyl)phenyl)amino)-5-oxopentanoate

Downstream raw materials:

C₁₉H₂₅N₃O₆*C₂HF₃O₂

C₂₆H₃₁N₅O₆

C₂₈H₃₅N₅O₆

C₂₅H₃₁N₅O₇