((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-acetic acid tert-butyl ester

Base Information

Chemical Name:((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-acetic acid tert-butyl ester
CAS No.:209258-90-2
Molecular Formula:C₂₃H₂₈N₂O₅
Molecular Weight:412.486
Hs Code.:

Synonyms:((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-acetic acid tert-butyl ester

Suppliers and Price of ((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-acetic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-acetic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-acetic acid tert-butyl ester

There total 1 articles about ((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-acetic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 2448-45-5
Cbz-D-Phe

: 27532-96-3
glycine tert-butyl ester hydrochloride

: 209258-90-2
((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-acetic acid tert-butyl ester

Guidance literature:: With dmap; WSC*HCl; TEA; benzotriazol-1-ol; In N,N-dimethyl-formamide; for 8h; Ambient temperature;
DOI:10.1248/cpb.46.867

Reference yield:

: 209258-90-2
((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-acetic acid tert-butyl ester

: 1020852-42-9
tert-butyl ((R)-2-amino-3-phenylpropionylamino)acetate

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1248/cpb.46.867

Reference yield:

: 209258-90-2
((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-acetic acid tert-butyl ester

: {(R)-3-Phenyl-2-[((S)-pyrrolidine-2-carbonyl)-amino]-propionylamino}-acetic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / Pd/C / methanol

2: WSC*HCl, HOBt*H₂O, DMAP, TEA / dimethylformamide / 8 h / Ambient temperature

3: H₂ / Pd/C / methanol

With dmap; WSC*HCl; TEA; hydrogen; benzotriazol-1-ol; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1248/cpb.46.867