Cyclopropanecarboxylic acid 1-phenyl-1-(2-pyrrol-1-yl-thiophen-3-yl)-meth-(E)-ylideneamide

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Chemical Name:Cyclopropanecarboxylic acid 1-phenyl-1-(2-pyrrol-1-yl-thiophen-3-yl)-meth-(E)-ylideneamide
CAS No.:153898-05-6
Molecular Formula:C₁₉H₁₆N₂OS
Molecular Weight:320.415
Hs Code.:

Synonyms:Cyclopropanecarboxylic acid 1-phenyl-1-(2-pyrrol-1-yl-thiophen-3-yl)-meth-(E)-ylideneamide

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Chemical Property of Cyclopropanecarboxylic acid 1-phenyl-1-(2-pyrrol-1-yl-thiophen-3-yl)-meth-(E)-ylideneamide

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Technology Process of Cyclopropanecarboxylic acid 1-phenyl-1-(2-pyrrol-1-yl-thiophen-3-yl)-meth-(E)-ylideneamide

There total 3 articles about Cyclopropanecarboxylic acid 1-phenyl-1-(2-pyrrol-1-yl-thiophen-3-yl)-meth-(E)-ylideneamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 4023-34-1
cyclopropanecarboxylic acid chloride

: 153898-02-3
phenyl-3-<2-(1-pyrrolyl)thienyl>methylenimine

: 153898-05-6
Cyclopropanecarboxylic acid 1-phenyl-1-(2-pyrrol-1-yl-thiophen-3-yl)-meth-(E)-ylideneamide

Guidance literature:: With triethylamine; In tetrahydrofuran; for 2h; Ambient temperature;

Reference yield:

: 4651-82-5
2-amino-3-cyanothiophene

: 153898-05-6
Cyclopropanecarboxylic acid 1-phenyl-1-(2-pyrrol-1-yl-thiophen-3-yl)-meth-(E)-ylideneamide

Guidance literature:: Multi-step reaction with 3 steps

1: AcOH / 1.5 h

2: 84 percent / diethyl ether / 16 h / Heating

3: 82 percent / Et₃N / tetrahydrofuran / 2 h / Ambient temperature

With acetic acid; triethylamine; In tetrahydrofuran; diethyl ether;

Reference yield:

: 63647-03-0
(pyrrolyl-1)-2 thiophene carbonitrile-3

: 153898-05-6
Cyclopropanecarboxylic acid 1-phenyl-1-(2-pyrrol-1-yl-thiophen-3-yl)-meth-(E)-ylideneamide

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / diethyl ether / 16 h / Heating

2: 82 percent / Et₃N / tetrahydrofuran / 2 h / Ambient temperature

With triethylamine; In tetrahydrofuran; diethyl ether;