3-chloro-1-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-3-(4-methoxyphenyl)-1,2-diazaprop-2-ene

Base Information

• Chemical Name: 3-chloro-1-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-3-(4-methoxyphenyl)-1,2-diazaprop-2-ene
• CAS No.: 488712-87-4
• Molecular Formula: C₁₀H₇Cl₂N₃OS₂
• Molecular Weight: 320.223
• Mol file: 488712-87-4.mol

Synonyms:3-chloro-1-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-3-(4-methoxyphenyl)-1,2-diazaprop-2-ene

Chemical Property of 3-chloro-1-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-3-(4-methoxyphenyl)-1,2-diazaprop-2-ene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-chloro-1-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-3-(4-methoxyphenyl)-1,2-diazaprop-2-ene

There total 1 articles about 3-chloro-1-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-3-(4-methoxyphenyl)-1,2-diazaprop-2-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

5-(4-methoxyphenyl)-1H-tetrazole (6926-51-8) + 4,5-dichloro-1,2,3-dithiazolium chloride (75318-43-3) → 3-chloro-1-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-3-(4-methoxyphenyl)-1,2-diazaprop-2-ene (488712-87-4)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 1.5h;

DOI:10.1039/b202211g

Reference yield: 99.0%

3-chloro-1-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-3-(4-methoxyphenyl)-1,2-diazaprop-2-ene (488712-87-4) → 2-(4-methoxyphenyl)-1,3,4-thiadiazole-5-carbonitrile (325732-37-4)

Guidance literature:

With triphenylphosphine; In dichloromethane; at 20 ℃; for 0.166667h;

DOI:10.1039/b203705j

Reference yield:

3-chloro-1-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-3-(4-methoxyphenyl)-1,2-diazaprop-2-ene (488712-87-4) → 2-(4-methoxyphenyl)-5-(tetrazol-5-yl)-1,3,4-thiadiazole (478242-26-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / Ph₃P / CH₂Cl₂ / 0.17 h / 20 °C

2: 100 percent / AlCl₃; NaN₃ / tetrahydrofuran / 24 h / Heating

With aluminium trichloride; sodium azide; triphenylphosphine; In tetrahydrofuran; dichloromethane;

DOI:10.1039/b203705j

upstream raw materials:

5-(4-methoxyphenyl)-1H-tetrazole

4,5-dichloro-1,2,3-dithiazolium chloride

Downstream raw materials:

2-(4-methoxyphenyl)-1,3,4-thiadiazole-5-carbonitrile

2-(4-methoxyphenyl)-5-(tetrazol-5-yl)-1,3,4-thiadiazole