1-(1-(but-3-enyl)-2-(2,2-diphenylvinylidene)cyclopropyl)-4-fluorobenzene

Base Information

• Chemical Name: 1-(1-(but-3-enyl)-2-(2,2-diphenylvinylidene)cyclopropyl)-4-fluorobenzene
• CAS No.: 1201909-53-6
• Molecular Formula: C₂₇H₂₃F
• Molecular Weight: 366.478
• Mol file: 1201909-53-6.mol

Synonyms:1-(1-(but-3-enyl)-2-(2,2-diphenylvinylidene)cyclopropyl)-4-fluorobenzene

Chemical Property of 1-(1-(but-3-enyl)-2-(2,2-diphenylvinylidene)cyclopropyl)-4-fluorobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(1-(but-3-enyl)-2-(2,2-diphenylvinylidene)cyclopropyl)-4-fluorobenzene

There total 2 articles about 1-(1-(but-3-enyl)-2-(2,2-diphenylvinylidene)cyclopropyl)-4-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-fluoro-4-(hexa-1,5-dien-2-yl)benzene (1210959-77-5) + 1,1-dibromo-2,2-diphenylcyclopropane (17343-74-7) → 1-(1-(but-3-enyl)-2-(2,2-diphenylvinylidene)cyclopropyl)-4-fluorobenzene (1201909-53-6)

Guidance literature:

With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 36h;

DOI:10.1021/ol902505p DOI:10.1021/ol902832s

Reference yield:

1,1-Diphenylethylene (530-48-3) → 1-(1-(but-3-enyl)-2-(2,2-diphenylvinylidene)cyclopropyl)-4-fluorobenzene (1201909-53-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium tert-butylate / pentane

2: tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide / tetrahydrofuran / 36 h / 20 °C

With potassium tert-butylate; tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide; In tetrahydrofuran; pentane;

DOI:10.1055/s-0030-1259715

Reference yield: 91.0%

1-(1-(but-3-enyl)-2-(2,2-diphenylvinylidene)cyclopropyl)-4-fluorobenzene (1201909-53-6) → 6-(diphenylmethylene)-1-(4-fluorophenyl)bicyclo[5.1.0]oct-3-ene

Guidance literature:

With di(rhodium)tetracarbonyl dichloride; carbon monoxide; In toluene; acetonitrile; at 100 ℃; for 0.5h; under 760.051 Torr;

DOI:10.1021/ol902505p

upstream raw materials:

1-fluoro-4-(hexa-1,5-dien-2-yl)benzene

1,1-dibromo-2,2-diphenylcyclopropane

1,1-Diphenylethylene

Downstream raw materials:

4-(2-(2,2-diphenylvinylidene)-1-(4-fluorophenyl)cyclopropyl)butan-1-ol

C₂₇H₂₄BrFO

C₂₇H₂₄FIO

C₃₉H₃₃FSe₂