2-(4-Chlorophenyl)-4,4-dimethyl-5-methyleneoxazoline

Base Information

Chemical Name:2-(4-Chlorophenyl)-4,4-dimethyl-5-methyleneoxazoline
CAS No.:247196-65-2
Molecular Formula:C₁₂H₁₂ClNO
Molecular Weight:221.686
Hs Code.:
DSSTox Substance ID:DTXSID901179114

Synonyms:SCHEMBL7023627;DNNIPGICOPJUKN-UHFFFAOYSA-N;DTXSID901179114;2-(4-chlorophenyl)-4,4-dimethyl-5-methyleneoxazoline;2-(4-Chlorophenyl)-4,5-dihydro-4,4-dimethyl-5-methyleneoxazole;247196-65-2

Suppliers and Price of 2-(4-Chlorophenyl)-4,4-dimethyl-5-methyleneoxazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-Chlorophenyl)-4,4-dimethyl-5-methyleneoxazoline

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:221.0607417
Heavy Atom Count:15
Complexity:301

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(C(=C)OC(=N1)C2=CC=C(C=C2)Cl)C

Technology Process of 2-(4-Chlorophenyl)-4,4-dimethyl-5-methyleneoxazoline

There total 4 articles about 2-(4-Chlorophenyl)-4,4-dimethyl-5-methyleneoxazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 123-86-4
acetic acid butyl ester

: 24911-15-7
4-chloro-N-(1,1-dimethylprop-2-ynyl)benzamide

: 247196-65-2
2-(4-chloro-phenyl)-4,4-dimethyl-5-methylene-4,5-dihydrooxazole

Guidance literature:: copper(I) chloride;

Reference yield: 88.0%

: 24911-15-7
4-chloro-N-(1,1-dimethylprop-2-ynyl)benzamide

: 247196-65-2
2-(4-chloro-phenyl)-4,4-dimethyl-5-methylene-4,5-dihydrooxazole

Guidance literature:: With copper(l) iodide; In 1,2-dichloro-ethane; Inert atmosphere; Reflux;
DOI:10.1039/c3ob42030b

Reference yield:

: 2978-58-7
1,1-dimethylprop-3-ynylamine

: 247196-65-2
2-(4-chloro-phenyl)-4,4-dimethyl-5-methylene-4,5-dihydrooxazole

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 20 °C / Inert atmosphere

2: copper(l) iodide / 1,2-dichloro-ethane / Inert atmosphere; Reflux

With copper(l) iodide; triethylamine; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1039/c3ob42030b