4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid

Base Information

• Chemical Name: 4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid
• CAS No.: 947698-91-1
• Molecular Formula: C₂₉H₂₉NO₆
• Molecular Weight: 487.552
• Mol file: 947698-91-1.mol

Synonyms:4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid

Chemical Property of 4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid

There total 1 articles about 4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]prop-1-enyl}benzeneacetic acid → 4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid (947698-91-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; dichloromethane; for 20h;

DOI:10.1002/hlca.200790107

Reference yield: 79.0%

4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid (947698-91-1) + O-(N-succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate (105832-38-0) → 4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid 2,5-dioxopyrrolyn-1-yl ester (947698-90-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

DOI:10.1002/hlca.200790107

Reference yield:

4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid (947698-91-1) + O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate (125700-67-6) → C35H32N4O6

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1002/hlca.200890008

Downstream raw materials:

4-{3-[1,2-dihydro-6,7-dimethoxy-3-(4-methoxyphenyl)-2-oxoquinolin-1-yl]propyl}benzeneacetic acid 2,5-dioxopyrrolyn-1-yl ester