N-((S)-1-(N-((S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)methylsulfonamido)-3-(1H-indol-3-yl)propan-2-yl)-4-methylbenzenesulfonamide

Base Information

Chemical Name:N-((S)-1-(N-((S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)methylsulfonamido)-3-(1H-indol-3-yl)propan-2-yl)-4-methylbenzenesulfonamide
CAS No.:1264149-17-8
Molecular Formula:C₃₀H₃₄N₄O₅S₂
Molecular Weight:594.756
Hs Code.:

Synonyms:N-((S)-1-(N-((S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)methylsulfonamido)-3-(1H-indol-3-yl)propan-2-yl)-4-methylbenzenesulfonamide

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Chemical Property of N-((S)-1-(N-((S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)methylsulfonamido)-3-(1H-indol-3-yl)propan-2-yl)-4-methylbenzenesulfonamide

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Technology Process of N-((S)-1-(N-((S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)methylsulfonamido)-3-(1H-indol-3-yl)propan-2-yl)-4-methylbenzenesulfonamide

There total 6 articles about N-((S)-1-(N-((S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)methylsulfonamido)-3-(1H-indol-3-yl)propan-2-yl)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1264148-96-0
(S)-methyl 2-(N-((S)-3-(1H-indol-3-yl)-2-(4-methylphenylsulfonamido)propyl)methylsulfonamido)-3-(1H-indol-3-yl)propanoate

: 1264149-17-8
N-((S)-1-(N-((S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)methylsulfonamido)-3-(1H-indol-3-yl)propan-2-yl)-4-methylbenzenesulfonamide

Guidance literature:: With lithium borohydride; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1002/asia.201000554

Reference yield:

: 7524-52-9,26988-71-6,5619-09-0,14907-27-8,41222-70-2,67557-19-1,109492-62-8
(S)-tryptophan methyl ester hydrochloride

: 1264149-17-8
N-((S)-1-(N-((S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)methylsulfonamido)-3-(1H-indol-3-yl)propan-2-yl)-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / tetrahydrofuran / 0.08 h / 0 °C

1.2: 0 - 60 °C

2.1: pyridine / 0 - 20 °C

3.1: lithium borohydride / tetrahydrofuran / 0 - 20 °C

With pyridine; lithium borohydride; triethylamine; In tetrahydrofuran;
DOI:10.1002/asia.201000554

Reference yield:

: 152873-15-9
(S)-3-((1-tosylaziridin-2-yl)methyl)-1H-indole

: 1264149-17-8
N-((S)-1-(N-((S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)methylsulfonamido)-3-(1H-indol-3-yl)propan-2-yl)-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / tetrahydrofuran / 0.08 h / 0 °C

1.2: 0 - 60 °C

2.1: pyridine / 0 - 20 °C

3.1: lithium borohydride / tetrahydrofuran / 0 - 20 °C

With pyridine; lithium borohydride; triethylamine; In tetrahydrofuran;
DOI:10.1002/asia.201000554