1,2-dihydro-2-methyl-4-(2-methylphenyl)-1-oxo-3-isoquinolinecarbonitrile

Base Information

Chemical Name:1,2-dihydro-2-methyl-4-(2-methylphenyl)-1-oxo-3-isoquinolinecarbonitrile
CAS No.:170639-94-8
Molecular Formula:C₁₈H₁₄N₂O
Molecular Weight:274.322
Hs Code.:

Synonyms:1,2-dihydro-2-methyl-4-(2-methylphenyl)-1-oxo-3-isoquinolinecarbonitrile

Suppliers and Price of 1,2-dihydro-2-methyl-4-(2-methylphenyl)-1-oxo-3-isoquinolinecarbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,2-dihydro-2-methyl-4-(2-methylphenyl)-1-oxo-3-isoquinolinecarbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,2-dihydro-2-methyl-4-(2-methylphenyl)-1-oxo-3-isoquinolinecarbonitrile

There total 2 articles about 1,2-dihydro-2-methyl-4-(2-methylphenyl)-1-oxo-3-isoquinolinecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 170639-93-7
N-(cyanomethyl)-N-methyl-2-(2-methylbenzoyl)benzamide

: 170639-94-8
1,2-dihydro-2-methyl-4-(2-methylphenyl)-1-oxo-3-isoquinolinecarbonitrile

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In toluene; for 5h; Heating;
DOI:10.1021/jm00016a014

Reference yield:

: 5469-51-2
methylbenzoyl-benzoic acid

: 170639-94-8
1,2-dihydro-2-methyl-4-(2-methylphenyl)-1-oxo-3-isoquinolinecarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) SOCl₂, DMF, 2.) Et₃N / 1.) CH₂Cl₂, RT, 2 h, 2.) CH₂Cl₂, RT, overnight

2: 92 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / toluene / 5 h / Heating

With thionyl chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; N,N-dimethyl-formamide; In toluene;
DOI:10.1021/jm00016a014