Technology Process of 2-nitro-3-benzyloxyacetophenone
There total 1 articles about 2-nitro-3-benzyloxyacetophenone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: H2SO4; water; HNO3 / -20 °C
2: sodium ethylate; ethanol; KI
With
ethanol; sulfuric acid; water; nitric acid; sodium ethanolate; potassium iodide;
- Guidance literature:
-
With
dioxane dibromide;
In
dichloromethane;
for 1.5h;
Ambient temperature;
DOI:10.1021/jo982321n
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 82 percent / Br2*dioxane / CH2Cl2 / 1.5 h / Ambient temperature
2: 21 percent / EtONa / ethanol / 2 h / Ambient temperature
3: 64 percent / TFA / 24 h / Ambient temperature
4: 61 percent / Hg(CN)2, K2CO3 / acetonitrile / 2 h / Ambient temperature
5: 92 percent / H2 / Pd/C / ethyl acetate; ethanol / 24 h / 760 Torr
6: EtONa / ethanol / 1 h
7: 1.) NaOH, 2.) AcOH / 1.) H2O, rt, 12 h, 2.) H2O, 50 deg C, 3 h
With
sodium hydroxide; hydrogen; sodium ethanolate; mercury(II) cyanide; dioxane dibromide; potassium carbonate; acetic acid; trifluoroacetic acid;
palladium on activated charcoal;
In
ethanol; dichloromethane; ethyl acetate; acetonitrile;
DOI:10.1021/jo982321n
