1-benzenesulfonylazetidine

Base Information

• Chemical Name: 1-benzenesulfonylazetidine
• CAS No.: 121819-13-4
• Molecular Formula: C₉H₁₁NO₂S
• Molecular Weight: 197.258
• Mol file: 121819-13-4.mol

Synonyms:1-benzenesulfonylazetidine

Chemical Property of 1-benzenesulfonylazetidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzenesulfonylazetidine

There total 3 articles about 1-benzenesulfonylazetidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.3%

N-(3-bromo-propyl)-benzenesulfonamide (3245-94-1) → 1-benzenesulfonylazetidine (121819-13-4)

Guidance literature:

With caesium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1002/jhet.5570450449

Reference yield: 19.5%

benzenesulfonamide (98-10-2) + propane-1,3-diol ditosylate (5469-66-9) → 1-benzenesulfonylazetidine (121819-13-4)

Guidance literature:

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In benzene; Heating;

Reference yield:

azetidine (503-29-7) + benzenesulfonyl chloride (98-09-9) → 1-benzenesulfonylazetidine (121819-13-4)

Guidance literature:

With alkaline solution;

upstream raw materials:

azetidine

benzenesulfonyl chloride

benzenesulfonamide

propane-1,3-diol ditosylate

Refernces

• 1、 Singh, Paramjit,Jain, Anupa. "Organic Synthesis Using PTC: Part 8 - Synthesis of Macrocylic Systems Containing Nitrogen and/or Oxygen as Heteroatom(s)". . p. 790 - 792. Retrieved 2007/10/02.