5-[4-(3-chloro-phenyl)-5-fluoro-benzothiazol-6-ylmethyl]-pyridin-2-ylamine

Base Information

Chemical Name:5-[4-(3-chloro-phenyl)-5-fluoro-benzothiazol-6-ylmethyl]-pyridin-2-ylamine
CAS No.:1155286-91-1
Molecular Formula:C₁₉H₁₃ClFN₃S
Molecular Weight:369.85
Hs Code.:

Synonyms:5-[4-(3-chloro-phenyl)-5-fluoro-benzothiazol-6-ylmethyl]-pyridin-2-ylamine

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Chemical Property of 5-[4-(3-chloro-phenyl)-5-fluoro-benzothiazol-6-ylmethyl]-pyridin-2-ylamine

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Technology Process of 5-[4-(3-chloro-phenyl)-5-fluoro-benzothiazol-6-ylmethyl]-pyridin-2-ylamine

There total 1 articles about 5-[4-(3-chloro-phenyl)-5-fluoro-benzothiazol-6-ylmethyl]-pyridin-2-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 827614-64-2
2-aminopyridine-5-boronic acid pinacol ester

: 1155287-84-5
6-bromomethyl-4-(3-chloro-phenyl)-5-fluoro-benzothiazole

: 1155286-91-1
5-[4-(3-chloro-phenyl)-5-fluoro-benzothiazol-6-ylmethyl]-pyridin-2-ylamine

Guidance literature:: With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; ethanol; water; at 80 ℃; for 4h; microwave irradiation;

Reference yield: 22.0%

: 1118-68-9
dimethylaminoacetic acid

: 1155286-91-1
5-[4-(3-chloro-phenyl)-5-fluoro-benzothiazol-6-ylmethyl]-pyridin-2-ylamine

: 1155286-93-3
N-{5-[4-(3-chlorophenyl)-5-fluorobenzothiazol-6-ylmethyl]pyridin-2-yl}-2-dimethylaminoacetamide

Guidance literature:: dimethylaminoacetic acid; With thionyl chloride; In dichloromethane; for 3h;

5-[4-(3-chloro-phenyl)-5-fluoro-benzothiazol-6-ylmethyl]-pyridin-2-ylamine; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; for 3h;