(Z)-N'-cyano-3-(1-cyclohexyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-N-(4-fluorophenyl)azetidine-1-carboximidamide

Base Information

Chemical Name:(Z)-N'-cyano-3-(1-cyclohexyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-N-(4-fluorophenyl)azetidine-1-carboximidamide
CAS No.:1025784-26-2
Molecular Formula:C₂₂H₂₃FN₈O
Molecular Weight:434.476
Hs Code.:

Synonyms:(Z)-N'-cyano-3-(1-cyclohexyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-N-(4-fluorophenyl)azetidine-1-carboximidamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-N'-cyano-3-(1-cyclohexyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-N-(4-fluorophenyl)azetidine-1-carboximidamide

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Technology Process of (Z)-N'-cyano-3-(1-cyclohexyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-N-(4-fluorophenyl)azetidine-1-carboximidamide

There total 2 articles about (Z)-N'-cyano-3-(1-cyclohexyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-N-(4-fluorophenyl)azetidine-1-carboximidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 643042-26-6
phenyl N'-cyano-N-(4-fluorophenyl)carbamimidate

: 1025712-97-3
6-azetidin-3-yl-1-cyclohexyl-1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one hydrochloride

: 1025784-26-2
(Z)-N'-cyano-3-(1-cyclohexyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-N-(4-fluorophenyl)azetidine-1-carboximidamide

Guidance literature:: With triethylamine; In isopropyl alcohol; at 50 ℃; for 16h;

Reference yield:

: 371-40-4
4-fluoroaniline

: 1025784-26-2
(Z)-N'-cyano-3-(1-cyclohexyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-N-(4-fluorophenyl)azetidine-1-carboximidamide

Guidance literature:: Multi-step reaction with 2 steps

1: isopropyl alcohol / 18 h / 20 °C

2: triethylamine / isopropyl alcohol / 16 h / 50 °C

With triethylamine; In isopropyl alcohol;