(1S,6R)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide

Base Information

Chemical Name:(1S,6R)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide
CAS No.:857682-03-2
Molecular Formula:C₁₆H₂₄N₂O₃S₂
Molecular Weight:356.51
Hs Code.:

Synonyms:(1S,6R)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide

Suppliers and Price of (1S,6R)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,6R)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,6R)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide

There total 3 articles about (1S,6R)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: racemic cis-6-(N-methoxy-N-methylaminocarbonyl)cyclohex-3-enecarboxylic acid

: 76186-04-4
(S)-4-isopropylthiazolidine-2-thione

: 857682-03-2
(1S,6R)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide

: (1R,6S)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 8h;
DOI:10.3987/COM-05-10356

Reference yield:

: 935-79-5
cis-1,2,3,6-tetrahydrophthalic anhydride

: 857682-03-2
(1S,6R)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: NaH / tetrahydrofuran; dimethylsulfoxide / 1 h / -50 - -40 °C

2: 56 percent / Et₃N / CH₂Cl₂ / 0.5 h / 20 °C

3: DMAP; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride / CH₂Cl₂ / 8 h / 20 °C

With dmap; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide;
DOI:10.3987/COM-05-10356

Reference yield:

: 6-((S)-4-Isopropyl-2-thioxo-thiazolidine-3-carbonyl)-cyclohex-3-enecarboxylic acid

: 857682-03-2
(1S,6R)-6-[(4S)-4-isopropyl-1,3-thiazolidine-2-thion-3-yl]carbonyl-N-methoxy-N-methylcyclohex-3-enecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 56 percent / Et₃N / CH₂Cl₂ / 0.5 h / 20 °C

2: DMAP; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride / CH₂Cl₂ / 8 h / 20 °C

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane;
DOI:10.3987/COM-05-10356