(R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyric acid 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyl ester

Base Information

• Chemical Name: (R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyric acid 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyl ester
• CAS No.: 215054-01-6
• Molecular Formula: C₂₂H₂₀F₁₃IN₂O₅
• Molecular Weight: 766.295
• Mol file: 215054-01-6.mol

Synonyms:(R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyric acid 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyl ester

Chemical Property of (R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyric acid 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyric acid 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyl ester

There total 1 articles about (R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyric acid 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.8%

n-perfluorohexyl iodide (355-43-1) + (R)-2-[(4aR,6S,7R,8R,8aS)-7-Acetylamino-2,2-dimethyl-6-(4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-propionic acid methyl ester (215052-76-9) → (R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyric acid 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyl ester (215054-01-6)

Guidance literature:

With sodium hydrogencarbonate; sodium sulfate; In water; acetonitrile; for 2h; Ambient temperature;

DOI:10.1016/S0040-4020(98)00738-8

Reference yield: 70.0%

(R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyric acid 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyl ester (215054-01-6) → (R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyric acid 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-nonyl ester (215052-98-5)

Guidance literature:

With hydrogen; diethylamine; palladium on activated charcoal; In ethanol; ethyl acetate; under 3800 Torr; Ambient temperature;

DOI:10.1016/S0040-4020(98)00738-8

upstream raw materials:

n-perfluorohexyl iodide

(R)-2-[(4aR,6S,7R,8R,8aS)-7-Acetylamino-2,2-dimethyl-6-(4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-propionic acid methyl ester

Downstream raw materials:

(R)-4-Benzyloxycarbonylamino-4-carbamoyl-butyric acid 4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-nonyl ester