355-43-1 Usage
Description
Perfluoro-1-iodohexane, also known as Perfluorohexyl Iodide, is a chemical compound with the formula C6F13I. It is a liquid at room temperature and forms 1:1 complexes with various hydrogen-bond acceptors. Perfluoro-1-iodohexane is an important intermediate in the synthesis of organic fluorides products and exhibits estrogenic activity in vitro.
Uses
1. Used in Organic Synthesis:
Perfluoro-1-iodohexane is used as an intermediate in the synthesis of organic fluorides for various applications, including pharmaceuticals and specialty chemicals.
2. Used in Polymer Modification:
Perfluoro-1-iodohexane is used as a grafting agent for the modification of polymers, such as poly(α-olefin) with fluorinated side chains, to enhance their properties like chemical resistance and thermal stability.
3. Used in Screening Assays:
Perfluoro-1-iodohexane is used as a screening agent for binding affinities of perfluoroalkyl iodide for estrogen receptor alpha and beta isoforms, which is important in the study of endocrine-disrupting chemicals and their potential health effects.
4. Used in Chemical Research:
The radical addition of perfluoro-1-iodohexane to vinyl acetate, using azo-bis(isobutyronitrile) (AIBN) as an initiator, has been investigated for understanding the reactivity and potential applications of this compound in chemical research and development.
Safety Profile
Explodes in contact with sodium when heated to the boiling point of the iodide. When heated to decomposition it emits toxic fumes of Fí and Ií.
Check Digit Verification of cas no
The CAS Registry Mumber 355-43-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,5 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 355-43:
(5*3)+(4*5)+(3*5)+(2*4)+(1*3)=61
61 % 10 = 1
So 355-43-1 is a valid CAS Registry Number.
InChI:InChI=1/C6F13I/c7-1(8,3(11,12)5(15,16)17)2(9,10)4(13,14)6(18,19)20
355-43-1Relevant articles and documents
PARTIALLY FLUORINATED COMPOUNDS
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Paragraph 00113-00114, (2014/07/07)
Described herein is a composition comprising a partially fluorinated compound selected from the group consisting of: (a) I(CF2)XCH2CF2I; (b) ICF2CH2(CF2)XCH2CF2I; (c) I(CF2)yCH=CF2; (d) CF2=CH(CF2)yCH2CF2I; and (e) CF2=CH(CF2)yCH=CF2 wherein x is an odd integer selected from 3 to 11, and y is an integer greater than 2, along with methods of making and polymerizing such compounds.
PROCESS FOR PRODUCING FLUOROALKYL IODIDE TELOMER
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Page/Page column 3-4, (2011/02/25)
A novel process for producing a fluoroalkyl iodide telomer is provided, which is able to obtain a fluoroalkyl iodide telomer having a desired chain length, efficiently. A fluoroalkyl iodide represented by the general formula RfI (wherein Rf is a C1-10 fluoroalkyl group) and tetrafluoroethylene are used as a telogen and a taxogen, respectively. These compounds are supplied to a distillation apparatus. In a reaction zone located in an intermediate part of the distillation apparatus, the compounds are subjected to a telomerization reaction in the presence of a metal catalyst with heating to generate a fluoroalkyl iodide telomer represented by the general formula Rf(CF2CF2)nI (wherein Rf is the same as defined above and n is an integer of 1-4). Thereafter, a fraction comprising the fluoroalkyl iodide telomer is separated by distillation.
Practical and efficient synthesis of perfluoroalkyl iodides from perfluoroalkyl chlorides via modified sulfinatodehalogenation
Cao, Hai-Ping,Chen, Qing-Yun
, p. 1187 - 1190 (2008/02/10)
A novel two-step one pot synthesis of perfluoroalkyl iodides (α,ω-diiodoperfluoroalkanes) from perfluoroalkyl chlorides (α-chloro-ω-iodoperfluoroalkanes) has been developed by initial conversion to the corresponding sodium perfluoroalkanesulfinates with sodium dithionite and then subsequent oxidation by iodine.
