(1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-(4-methoxyphenyl)ethylboronic acid (+)-pinanediol ester

Base Information

Chemical Name:(1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-(4-methoxyphenyl)ethylboronic acid (+)-pinanediol ester
CAS No.:1158974-98-1
Molecular Formula:C₃₉H₅₆BN₃O₈
Molecular Weight:705.7
Hs Code.:

Synonyms:(1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-(4-methoxyphenyl)ethylboronic acid (+)-pinanediol ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-(4-methoxyphenyl)ethylboronic acid (+)-pinanediol ester

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Technology Process of (1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-(4-methoxyphenyl)ethylboronic acid (+)-pinanediol ester

There total 1 articles about (1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-(4-methoxyphenyl)ethylboronic acid (+)-pinanediol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1158974-97-0
Boc-Tyr(Me)-Val-OH

: 1158974-86-7
(1R)-1-amino-2-(4-methoxyphenyl)-ethylboronic acid (+)-pinanediol ester trifluoroacetate

: 1158974-98-1
(1R)-1-(N-tert-butoxycarbonyl-L-O-methyltyrosyl-L-valyl)amino-2-(4-methoxyphenyl)ethylboronic acid (+)-pinanediol ester

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 20h;
DOI:10.1016/j.bmcl.2009.02.117