N-[4-(8-acetylaminoquinolin-4-yloxy)phenyl]-4-chloro-3-trifluoro-methylbenzamide

Base Information

Chemical Name:N-[4-(8-acetylaminoquinolin-4-yloxy)phenyl]-4-chloro-3-trifluoro-methylbenzamide
CAS No.:1174996-92-9
Molecular Formula:C₂₅H₁₇ClF₃N₃O₃
Molecular Weight:499.876
Hs Code.:

Synonyms:N-[4-(8-acetylaminoquinolin-4-yloxy)phenyl]-4-chloro-3-trifluoro-methylbenzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-(8-acetylaminoquinolin-4-yloxy)phenyl]-4-chloro-3-trifluoro-methylbenzamide

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Technology Process of N-[4-(8-acetylaminoquinolin-4-yloxy)phenyl]-4-chloro-3-trifluoro-methylbenzamide

There total 2 articles about N-[4-(8-acetylaminoquinolin-4-yloxy)phenyl]-4-chloro-3-trifluoro-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.3%

: 1174996-92-9
N-[4-(8-acetylaminoquinolin-4-yloxy)phenyl]-4-chloro-3-trifluoro-methylbenzamide

Guidance literature:

Reference yield: 41.0%

: 1174996-91-8
N-[4-(8-aminoquinolin-4-yloxy)phenyl]-4-chloro-3-trifluoromethyl-benzamide

: 64-19-7,77671-22-8
acetic acid

: 1174996-92-9
N-[4-(8-acetylaminoquinolin-4-yloxy)phenyl]-4-chloro-3-trifluoro-methylbenzamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 12h;
DOI:10.1016/j.bmcl.2009.05.007