N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-8-[(4-imidazolyl)methylamino]-2'-deoxyadenosine

Base Information

• Chemical Name: N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-8-[(4-imidazolyl)methylamino]-2'-deoxyadenosine
• CAS No.: 1093660-15-1
• Molecular Formula: C₄₂H₄₀N₈O₆
• Molecular Weight: 752.83

Synonyms:N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-8-[(4-imidazolyl)methylamino]-2'-deoxyadenosine

Chemical Property of N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-8-[(4-imidazolyl)methylamino]-2'-deoxyadenosine

Chemical Property:

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Technology Process of N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-8-[(4-imidazolyl)methylamino]-2'-deoxyadenosine

There total 1 articles about N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-8-[(4-imidazolyl)methylamino]-2'-deoxyadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

imidazole-4-methanamine dihydrochloride (66247-84-5,72631-80-2) + N-(9-{5-[bis(4-methoxyphenyl)phenylmethoxyphenyl]-4-hydroxytetrahydrofuran-2-yl}-8-bromo-9H-purin-6-yl)benzamide (129451-79-2) → N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-8-[(4-imidazolyl)methylamino]-2'-deoxyadenosine (1093660-15-1)

Guidance literature:

With triethylamine; In ethanol; at 65 ℃; for 4.5h;

DOI:10.1002/ejoc.200800381

upstream raw materials:

imidazole-4-methanamine dihydrochloride

N-(9-{5-[bis(4-methoxyphenyl)phenylmethoxyphenyl]-4-hydroxytetrahydrofuran-2-yl}-8-bromo-9H-purin-6-yl)benzamide

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