N-methyl-N-(4-methylbenzoylmethyl)-1,2,3,4-tetrahydroisoquinolinium bromide

Base Information

Chemical Name:N-methyl-N-(4-methylbenzoylmethyl)-1,2,3,4-tetrahydroisoquinolinium bromide
CAS No.:1416151-77-3
Molecular Formula:Br*C₁₉H₂₂NO
Molecular Weight:360.294
Hs Code.:

Synonyms:N-methyl-N-(4-methylbenzoylmethyl)-1,2,3,4-tetrahydroisoquinolinium bromide

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Chemical Property of N-methyl-N-(4-methylbenzoylmethyl)-1,2,3,4-tetrahydroisoquinolinium bromide

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Technology Process of N-methyl-N-(4-methylbenzoylmethyl)-1,2,3,4-tetrahydroisoquinolinium bromide

There total 2 articles about N-methyl-N-(4-methylbenzoylmethyl)-1,2,3,4-tetrahydroisoquinolinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1612-65-3
2-methyl-1,2,3,4-tetrahydroisoquinoline

: 619-41-0
4-(bromoacetyl)toluene

: 1416151-77-3
N-methyl-N-(4-methylbenzoylmethyl)-1,2,3,4-tetrahydroisoquinolinium bromide

Guidance literature:: In tetrahydrofuran; for 2h; Inert atmosphere; Reflux;
DOI:10.1007/s10593-012-1141-9

Reference yield:

: 91-21-4
1,2,3,4-tetrahydroisoquinoline

: 1416151-77-3
N-methyl-N-(4-methylbenzoylmethyl)-1,2,3,4-tetrahydroisoquinolinium bromide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide

2: tetrahydrofuran / 2 h / Inert atmosphere; Reflux

With potassium hydroxide; In tetrahydrofuran;
DOI:10.1007/s10593-012-1141-9