Technology Process of C50H50Cl6O16S
There total 4 articles about C50H50Cl6O16S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: NaOH / tetrahydrofuran; H2O / 0.33 h / Ambient temperature
2: 5.55 g / dicyclohexylcarbodiimide, 4-N,N-dimethylaminopyridine / toluene / 0.17 h / Ambient temperature
3: 76 percent / hexamethylphosphoramide, TiBr4 / CH2Cl2 / 18 h / 0 °C
4: 1.) NaH / 1.) DMF, 30 min, 2.) DMF, -10 deg C, 30 min
With
N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; sodium hydroxide; titanium(IV) bromide; sodium hydride; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; dichloromethane; water; toluene;
DOI:10.1016/S0040-4020(98)01108-9
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 76 percent / hexamethylphosphoramide, TiBr4 / CH2Cl2 / 18 h / 0 °C
2: 1.) NaH / 1.) DMF, 30 min, 2.) DMF, -10 deg C, 30 min
With
N,N,N,N,N,N-hexamethylphosphoric triamide; titanium(IV) bromide; sodium hydride;
In
dichloromethane;
DOI:10.1016/S0040-4020(98)01108-9
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 5.55 g / dicyclohexylcarbodiimide, 4-N,N-dimethylaminopyridine / toluene / 0.17 h / Ambient temperature
2: 76 percent / hexamethylphosphoramide, TiBr4 / CH2Cl2 / 18 h / 0 °C
3: 1.) NaH / 1.) DMF, 30 min, 2.) DMF, -10 deg C, 30 min
With
N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; titanium(IV) bromide; sodium hydride; dicyclohexyl-carbodiimide;
In
dichloromethane; toluene;
DOI:10.1016/S0040-4020(98)01108-9
