(-)-(α)-<<<2-(3,4-dimethoxyphenyl)ethyl>amino>methyl>-(α)-<(1,1-dimethylethyl)dimethylsilyloxy>-4-(2-propenyloxy)benzenemethane

Base Information

Chemical Name:(-)-(α)-<<<2-(3,4-dimethoxyphenyl)ethyl>amino>methyl>-(α)-<(1,1-dimethylethyl)dimethylsilyloxy>-4-(2-propenyloxy)benzenemethane
CAS No.:153225-90-2
Molecular Formula:C₂₇H₄₁NO₄Si
Molecular Weight:471.712
Hs Code.:

Synonyms:(-)-(α)-<<<2-(3,4-dimethoxyphenyl)ethyl>amino>methyl>-(α)-<(1,1-dimethylethyl)dimethylsilyloxy>-4-(2-propenyloxy)benzenemethane

Suppliers and Price of (-)-(α)-<<<2-(3,4-dimethoxyphenyl)ethyl>amino>methyl>-(α)-<(1,1-dimethylethyl)dimethylsilyloxy>-4-(2-propenyloxy)benzenemethane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-(α)-<<<2-(3,4-dimethoxyphenyl)ethyl>amino>methyl>-(α)-<(1,1-dimethylethyl)dimethylsilyloxy>-4-(2-propenyloxy)benzenemethane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-(α)-<<<2-(3,4-dimethoxyphenyl)ethyl>amino>methyl>-(α)-<(1,1-dimethylethyl)dimethylsilyloxy>-4-(2-propenyloxy)benzenemethane

There total 3 articles about (-)-(α)-<<<2-(3,4-dimethoxyphenyl)ethyl>amino>methyl>-(α)-<(1,1-dimethylethyl)dimethylsilyloxy>-4-(2-propenyloxy)benzenemethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40663-68-1
4-(2-propenyloxy)benzaldehyde

: 153225-90-2
(-)-(α)-<<<2-(3,4-dimethoxyphenyl)ethyl>amino>methyl>-(α)-<(1,1-dimethylethyl)dimethylsilyloxy>-4-(2-propenyloxy)benzenemethane

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / (S,S)-cyclo(phenylalanylhistidyl) / toluene / 36 h / -15 °C

2: 97 percent / imidazole / dimethylformamide / 1 h / Ambient temperature

3: 1.) DIBAL; NH₄Br, 3.) NaBH₄ / 1.) toluene, ether, -70 deg C, 3 h; MeOH, -60 to -70 deg C, 10 min, 2.) toluene, MeOH, -70 deg C to room temp., 40 min, 3.) toluene, MeOH, 0 deg C to room temp., overnight

With 1H-imidazole; sodium tetrahydroborate; (S,S)-cyclo(phenylalanylhistidyl); diisobutylaluminium hydride; ammonium bromide; In N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0040-4020(01)85686-6

Reference yield:

: 153225-88-8
2-hydroxy-2-<4-(2-propenyloxy)phenyl>acetonitrile

: 153225-90-2
(-)-(α)-<<<2-(3,4-dimethoxyphenyl)ethyl>amino>methyl>-(α)-<(1,1-dimethylethyl)dimethylsilyloxy>-4-(2-propenyloxy)benzenemethane

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / imidazole / dimethylformamide / 1 h / Ambient temperature

2: 1.) DIBAL; NH₄Br, 3.) NaBH₄ / 1.) toluene, ether, -70 deg C, 3 h; MeOH, -60 to -70 deg C, 10 min, 2.) toluene, MeOH, -70 deg C to room temp., 40 min, 3.) toluene, MeOH, 0 deg C to room temp., overnight

With 1H-imidazole; sodium tetrahydroborate; diisobutylaluminium hydride; ammonium bromide; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)85686-6

Reference yield:

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 153225-89-9
(R)-2-<(1,1-dimethylethyl)dimethylsilyloxy>-2-<4-(2-propenyloxy)phenyl>acetonitrile

: 153225-90-2
(-)-(α)-<<<2-(3,4-dimethoxyphenyl)ethyl>amino>methyl>-(α)-<(1,1-dimethylethyl)dimethylsilyloxy>-4-(2-propenyloxy)benzenemethane

Guidance literature:: With sodium tetrahydroborate; diisobutylaluminium hydride; Yield given. Multistep reaction;
DOI:10.1016/S0957-4166(00)80062-2