propyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

Base Information

Chemical Name:propyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate
CAS No.:1201648-48-7
Molecular Formula:C₂₄H₂₉ClN₂O₄
Molecular Weight:444.958
Hs Code.:

Synonyms:propyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

Suppliers and Price of propyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of propyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

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Technology Process of propyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

There total 3 articles about propyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71-23-8
propan-1-ol

: 1058165-14-2
R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetic acid

: 1201648-48-7
propyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

Guidance literature:: propan-1-ol; R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetic acid; With sulfuric acid; for 1h;

In water; toluene; pH=8 - 9; Product distribution / selectivity; Alkaline conditions;

Reference yield:

: 163837-57-8
(R)-(4-chlorophenyl)(phenyl)methylamine

: 1201648-48-7
propyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-ethyl-N,N-diisopropylamine / 3 h / Reflux

1.2: 60 °C / Reflux

2.1: tetrabutylammomium bromide / dimethyl sulfoxide / 10 h

3.1: sulfuric acid / 1 h

3.2: pH 8 - 9 / Alkaline conditions

With sulfuric acid; tetrabutylammomium bromide; N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide;

Reference yield:

: 300543-56-0
(R)-1-((4-chlorophenyl)(phenyl)methyl)piperazine

: 1201648-48-7
propyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrabutylammomium bromide / dimethyl sulfoxide / 10 h

2.1: sulfuric acid / 1 h

2.2: pH 8 - 9 / Alkaline conditions

With sulfuric acid; tetrabutylammomium bromide; In dimethyl sulfoxide;