Technology Process of 2-TRIFLUOROMETHYLPHENYLMETHYLSULFONE
There total 3 articles about 2-TRIFLUOROMETHYLPHENYLMETHYLSULFONE which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-((2-(trifluoromethyl)phenyl)sulfonyl)-1H-pyrrole;
With
(4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
water; acetonitrile;
at 20 ℃;
for 16h;
Inert atmosphere;
Sealed tube;
Irradiation;
methyl iodide;
With
sodium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1002/chem.202102748
- Guidance literature:
-
With
1-benzylimidazole; copper diacetate; potassium carbonate;
4 A molecular sieve;
In
dimethyl sulfoxide;
at 60 ℃;
for 22h;
DOI:10.1021/ol071396n
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: p-toluenesulfonic acid monohydrate / toluene / 0.5 h / 20 - 100 °C / Inert atmosphere
2.1: N-ethyl-N,N-diisopropylamine; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate / acetonitrile; water / 16 h / 20 °C / Inert atmosphere; Sealed tube; Irradiation
2.2: 2 h / 20 °C / Inert atmosphere
With
(4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; p-toluenesulfonic acid monohydrate; N-ethyl-N,N-diisopropylamine;
In
water; toluene; acetonitrile;
DOI:10.1002/chem.202102748
