8-chloro-N'-(2-chloro-5-fluoro-4-methoxybenzoyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide

Base Information

Chemical Name:8-chloro-N'-(2-chloro-5-fluoro-4-methoxybenzoyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide
CAS No.:1228376-41-7
Molecular Formula:C₁₇H₁₀Cl₂F₄N₄O₃
Molecular Weight:465.191
Hs Code.:

Synonyms:8-chloro-N'-(2-chloro-5-fluoro-4-methoxybenzoyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide

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Chemical Property of 8-chloro-N'-(2-chloro-5-fluoro-4-methoxybenzoyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide

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Technology Process of 8-chloro-N'-(2-chloro-5-fluoro-4-methoxybenzoyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide

There total 1 articles about 8-chloro-N'-(2-chloro-5-fluoro-4-methoxybenzoyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.13%

: 883032-94-8
8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide

: 2-chloro-4-methoxy-5-fluorobenzoic acid

: 1228376-41-7
8-chloro-N'-(2-chloro-5-fluoro-4-methoxybenzoyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 - 100 ℃; for 15h;

Reference yield: 39.6%

: 1228376-41-7
8-chloro-N'-(2-chloro-5-fluoro-4-methoxybenzoyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide

: 1228375-40-3
2-(2-chloro-5-fluoro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,3,4-thiadiazole

Guidance literature:: 8-chloro-N'-(2-chloro-5-fluoro-4-methoxybenzoyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide; With Lawessons reagent; pyridine; In toluene; at 120 ℃; for 4h;

With pyridine; tetraphosphorus decasulfide; at 120 ℃; for 4h;