5-ACETYL-2,3-DIMETHYLFURAN

Base Information

• Chemical Name: 5-ACETYL-2,3-DIMETHYLFURAN
• CAS No.: 73761-44-1
• Molecular Formula: C8H10 O2
• Molecular Weight: 138.16
• Mol file: 73761-44-1.mol

Synonyms:2-Acetyl-4,5-dimethylfuran;5-Acetyl-2,3-dimethylfuran

Chemical Property of 5-ACETYL-2,3-DIMETHYLFURAN

Chemical Property:

• Vapor Pressure: 0.099mmHg at 25°C
• Refractive Index: 1.473
• Boiling Point: 222.882°C at 760 mmHg
• Flash Point: 96.048°C
• PSA: 30.21000
• Density: 1.014g/cm³
• LogP: 2.09900

Purity/Quality:

98%Min ^*data from raw suppliers

1-(4,5-dimethylfuran-2-yl)ethan-1-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-ACETYL-2,3-DIMETHYLFURAN

There total 7 articles about 5-ACETYL-2,3-DIMETHYLFURAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4,5-dihydroxy-3,4,5-trimethyl-cyclopent-2-en-1-one (97072-95-2) → 2-acetyl-4,5-dimethylfuran (73761-44-1)

Guidance literature:

With sulfuric acid; for 48h; Ambient temperature;

DOI:10.1021/jo00217a005

Reference yield:

2,3,6-trimethyl-4H-pyran-4-one (13519-43-2) → 2-acetyl-4,5-dimethylfuran (73761-44-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 63 percent / 50percent aq. H₂SO₄ / 0 °C / Irradiation

2: 85 percent / 50percent aq. H₂SO₄ / 48 h / Ambient temperature

With sulfuric acid;

DOI:10.1021/jo00217a005

Reference yield:

2,3,6-trimethyl-4H-pyran-4-one (13519-43-2) → 4,5,6-trimethyl-2H-pyran-2-one (14818-31-6) + 2-acetyl-4,5-dimethylfuran (73761-44-1)

Guidance literature:

With sulfuric acid; Ambient temperature; Irradiation;

DOI:10.1021/jo00217a005

upstream raw materials:

2,3-dimethylfuran

N,N-dimethyl acetamide

2,3,6-trimethyl-4H-pyran-4-one

4,5-dihydroxy-3,4,5-trimethyl-cyclopent-2-en-1-one

Downstream raw materials:

2-(N-isopropylbenzyl)aminoethyl-4,5-dimethyl-2-furylketone

2-(N-2-hydroxyethylbenzyl)aminoethyl-4,5-dimethyl-2-furylketone

Refernces

• 1、 Vegh, Daniel,Zalupsky, Peter,Kovac, Jaroslav. "A SHORT, EFFICIENT, MULTIGRAM SYNTHETIC ROUTE TO 2,3-DIMETHYLFURAN AND SOME OF ITS 2-SUBSTITUTED DERIVATIVES". . p. 1113 - 1123. Retrieved 2007/10/02.
• 2、 Pavlik, James W.,Snead, Thomas E.,Tata, James R.. "Photochemistry of 4-Pyrones in Water. Formation of Dihydroxycyclopentenones and Furan Derivatives". . p. 1481 - 1483. Retrieved 2007/10/02.