2,3-DIMETHYLFURAN

Base Information

• Chemical Name: 2,3-DIMETHYLFURAN
• CAS No.: 14920-89-9
• Molecular Formula: C6H8 O
• Molecular Weight: 96.1289
• Hs Code.: 29321900
• European Community (EC) Number: 249-235-2,626-651-6
• DSSTox Substance ID: DTXSID301027759
• Nikkaji Number: J498.240A
• Wikidata: Q82001890
• ChEMBL ID: CHEMBL108232
• Mol file: 14920-89-9.mol

Synonyms:2,3-Dimethylfuran

Chemical Property of 2,3-DIMETHYLFURAN

Chemical Property:

• Vapor Pressure: 41.3mmHg at 25°C
• Melting Point: -62.8°C (estimate)
• Refractive Index: n20/D 1.443(lit.)
• Boiling Point: 42℃115mmHg(lit.)
• Flash Point: 30℉
• PSA: 13.14000
• Density: 0.91g/mLat25℃(lit.)
• LogP: 1.89640
• Storage Temp.: Flammables area
• Water Solubility.: Insoluble in water.
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 96.057514874
• Heavy Atom Count: 7
• Complexity: 61.2

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,3-Dimethylfuran ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 11-20/21/22
• Safety Statements: 16-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=C(OC=C1)C
• Uses: 2,3-Dimethylfuran may be used in the synthesis of 2,9-dioxabicyclo[3.3.1]nonane. Ireland Alcohol was synthesized in from 2,3-dimethylfuran.

Technology Process of 2,3-DIMETHYLFURAN

There total 22 articles about 2,3-DIMETHYLFURAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(Z)-3-methylpent-2-en-4-ynol (6153-05-5,105-29-3) → 2,3-dimethylfuran (14920-89-9)

Guidance literature:

With [Au₂Cl₂(μ-1,1′-bis(ditert-butylphosphino)ferrocene)]; In chloroform-d1; 1,2-dichloro-ethane; at 20 ℃; for 3h; Reagent/catalyst; Catalytic behavior; Inert atmosphere;

DOI:10.1016/j.jorganchem.2019.03.006

Reference yield: 82.0%

methanol (67-56-1) + (Z)-3-methylpent-2-en-4-ynol (6153-05-5,105-29-3) + carbon monoxide (201230-82-2) → 2,3-dimethylfuran (14920-89-9) + methyl (3-methylfuran-2-yl)acetate (149694-49-5)

Guidance literature:

With potassium iodide; palladium(II) iodide; In methanol; at 70 ℃; for 15h; under 76000 Torr;

DOI:10.1016/S0040-4039(97)01584-0

Reference yield: 78.0%

3-methylpent-2-en-4-yn-1-ol (6153-06-6,105-29-3) → 2,3-dimethylfuran (14920-89-9)

Guidance literature:

With gold(III) tribromide; In 1,2-dichloro-ethane; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/S1872-2067(15)60994-9

upstream raw materials:

4,5-dimethyl-furan-2-carboxylic acid

2-methylfuran

Methyl fluoride

methyl iodide

Downstream raw materials:

2-acetyl-4,5-dimethylfuran

ethyl 4,5-dimethylfuroate

(1S,2S,3R,4R)-5-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-1-(4,5-dimethyl-furan-2-yl)-2,4-dimethyl-pentan-1-ol

(1R,2S,3R,4R)-5-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-1-(4,5-dimethyl-furan-2-yl)-2,4-dimethyl-pentan-1-ol