1-(4-chlorophenyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine trifluoroacetate

Base Information

Chemical Name:1-(4-chlorophenyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine trifluoroacetate
CAS No.:1334711-87-3
Molecular Formula:C₂HF₃O₂*C₁₈H₁₈ClN₃
Molecular Weight:425.838
Hs Code.:

Synonyms:1-(4-chlorophenyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine trifluoroacetate

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Chemical Property of 1-(4-chlorophenyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine trifluoroacetate

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Technology Process of 1-(4-chlorophenyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine trifluoroacetate

There total 5 articles about 1-(4-chlorophenyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1334711-85-1
tert-butyl 4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidine-1-carboxylate

: 1334711-87-3
1-(4-chlorophenyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine trifluoroacetate

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 271-29-4
6-azaindole

: 1334711-87-3
1-(4-chlorophenyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1: potassium hydroxide / methanol / Reflux

2: cyclohexene / palladium 10% on activated carbon / ethanol / 0.42 h / 150 °C / Microwave irradiation

3: potassium phosphate / copper(l) iodide; N,N-dimethylethylenediamine / toluene / 72 h / 110 °C

4: dichloromethane / 2 h

With potassium phosphate; potassium hydroxide; cyclohexene; copper(l) iodide; palladium 10% on activated carbon; N,N-dimethylethylenediamine; In methanol; ethanol; dichloromethane; toluene; 3: Buchwald-Hartwig Reaction;

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 1334711-87-3
1-(4-chlorophenyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1: potassium hydroxide / methanol / Reflux

2: cyclohexene / palladium 10% on activated carbon / ethanol / 0.42 h / 150 °C / Microwave irradiation

3: potassium phosphate / copper(l) iodide; N,N-dimethylethylenediamine / toluene / 72 h / 110 °C

4: dichloromethane / 2 h

With potassium phosphate; potassium hydroxide; cyclohexene; copper(l) iodide; palladium 10% on activated carbon; N,N-dimethylethylenediamine; In methanol; ethanol; dichloromethane; toluene; 3: Buchwald-Hartwig Reaction;