4-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide

Base Information

• Chemical Name: 4-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide
• CAS No.: 750597-06-9
• Molecular Formula: C₁₁H₁₀F₃N₃O₂S
• Molecular Weight: 305.281
• Mol file: 750597-06-9.mol

Synonyms:4-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide

Chemical Property of 4-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide

There total 1 articles about 4-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1,1,1-Trifluoro-2,4-pentanedione (367-57-7) + 4-hydrazinobenzene-1-sulfonamide hydrochloride (17852-52-7,27918-19-0) → 4-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide (750597-06-9)

Guidance literature:

In ethanol; for 4h; Reflux;

DOI:10.1016/j.jfluchem.2010.12.009

Reference yield: 80.0%

4-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide (750597-06-9) → C11H9BrF3N3O2S (1274724-20-7)

Guidance literature:

With bromine; In chloroform; for 1h; Reflux;

DOI:10.1016/j.jfluchem.2010.12.009

Reference yield: 78.0%

phenyl isothiocyanate (103-72-0) + 4-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide (750597-06-9) → C18H15F3N4O2S2

Guidance literature:

With potassium carbonate; In acetone; for 10h; Heating;

upstream raw materials:

1,1,1-Trifluoro-2,4-pentanedione

4-hydrazinobenzene-1-sulfonamide hydrochloride

Downstream raw materials:

C₁₉H₁₇F₃N₄O₂S₂

C₁₈H₁₄ClF₃N₄O₃S

C₁₈H₁₄BrF₃N₄O₃S

C₁₈H₁₃BrClF₃N₄O₃S