5-(but-3-ent-1-sulfonyl)-1-phenyl-1H-tetrazole

Base Information

• Chemical Name: 5-(but-3-ent-1-sulfonyl)-1-phenyl-1H-tetrazole
• CAS No.: 717124-35-1
• Molecular Formula: C₁₁H₁₂N₄O₂S
• Molecular Weight: 264.308
• Mol file: 717124-35-1.mol

Synonyms:5-(but-3-ent-1-sulfonyl)-1-phenyl-1H-tetrazole

Chemical Property of 5-(but-3-ent-1-sulfonyl)-1-phenyl-1H-tetrazole

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 5-(but-3-ent-1-sulfonyl)-1-phenyl-1H-tetrazole

There total 1 articles about 5-(but-3-ent-1-sulfonyl)-1-phenyl-1H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

5-(but-3-en-1-ylthio)-1-phenyl-1H tetrazole (936642-34-1) → 5-(but-3-ent-1-sulfonyl)-1-phenyl-1H-tetrazole (717124-35-1)

Guidance literature:

With ammonium molybdate; dihydrogen peroxide; In ethanol; at 20 ℃; for 6h;

DOI:10.1002/chem.200305634

Reference yield: 81.0%

C14H24O4 (936642-17-0) + 5-(but-3-ent-1-sulfonyl)-1-phenyl-1H-tetrazole (717124-35-1) → 2-((4aS,5S,7S,8aR)-2,2,4a-trimethyl-7-((E)-4-((1-phenyl-1H-tetrazol-5-yl)sulfonyl)but-1-en-1-yl)hexahydropyrano[4,3-d]-[1,3]dioxin-5-yl)ethanol (936642-18-1)

Guidance literature:

tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 45 ℃; for 22h;

DOI:10.1021/ol0701013

Reference yield:

5-(but-3-ent-1-sulfonyl)-1-phenyl-1H-tetrazole (717124-35-1) → C25H36N4O6S2 (936642-05-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / 2nd generation Grubbs' catalyst / CH₂Cl₂ / 22 h / 45 °C

2: 88 percent / benzoyl peroxide / acetonitrile / 1 h / 0 - 20 °C

With dibenzoyl peroxide; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; acetonitrile;

DOI:10.1021/ol0701013

upstream raw materials:

5-(but-3-en-1-ylthio)-1-phenyl-1H tetrazole

Downstream raw materials:

2-((4aS,5S,7S,8aR)-2,2,4a-trimethyl-7-((E)-4-((1-phenyl-1H-tetrazol-5-yl)sulfonyl)but-1-en-1-yl)hexahydropyrano[4,3-d]-[1,3]dioxin-5-yl)ethanol

C₂₅H₃₆N₄O₆S₂