C₁₆H₁₃BrO

Base Information

• Chemical Name: C₁₆H₁₃BrO
• CAS No.: 802925-20-8
• Molecular Formula: C₁₆H₁₃BrO
• Molecular Weight: 301.183
• Mol file: 802925-20-8.mol

Synonyms:C₁₆H₁₃BrO

Chemical Property of C₁₆H₁₃BrO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₁₃BrO

There total 2 articles about C₁₆H₁₃BrO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-methylstyrene (100-80-1) + carbon monoxide (201230-82-2) + 3-bromophenyl trifluoromethanesulfonate (66107-31-1) → C16H13BrO (802925-20-8)

Guidance literature:

With palladium diacetate; caesium carbonate; In water; at 35 - 95 ℃; for 13h; under 3750.38 Torr; Schlenk technique; Inert atmosphere;

DOI:10.1039/c8cc00324f

Reference yield:

1-(3-Bromophenyl)ethanone (2142-63-4) + m-tolyl aldehyde (620-23-5) → C16H13BrO (802925-20-8)

Guidance literature:

With sodium hydroxide;

DOI:10.1016/j.bmcl.2008.07.109

Reference yield:

C16H13BrO (802925-20-8) → C16H15BrO

Guidance literature:

With sodium tetrahydroborate; In methanol;

DOI:10.1016/j.bmcl.2008.07.109

upstream raw materials:

1-(3-Bromophenyl)ethanone

m-tolyl aldehyde

3-methylstyrene

carbon monoxide

Refernces

• 1、 Ellsworth, Bruce A.,Meng, Wei,Patel, Manorama,Girotra, Ravindar N.,Wu, Gang,Sher, Philip M.,Hagan, Deborah L.,Obermeier, Mary T.,Humphreys, William G.,Robertson, James G.,Wang, Aiying,Han, Songping,Waldron, Thomas L.,Morgan, Nathan N.,Whaley, Jean M.,Washburn, William N.. "Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2". scheme or table. p. 4770 - 4773. Retrieved 2009/05/07.