(1R,2R)-1,2-N,N'-bis(4-methoxyphenylamino)-1,2-diphenylethane

Base Information

• Chemical Name: (1R,2R)-1,2-N,N'-bis(4-methoxyphenylamino)-1,2-diphenylethane
• CAS No.: 170209-09-3
• Molecular Formula: C₂₈H₂₈N₂O₂
• Molecular Weight: 424.543
• Mol file: 170209-09-3.mol

Synonyms:(1R,2R)-1,2-N,N'-bis(4-methoxyphenylamino)-1,2-diphenylethane

Chemical Property of (1R,2R)-1,2-N,N'-bis(4-methoxyphenylamino)-1,2-diphenylethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2R)-1,2-N,N'-bis(4-methoxyphenylamino)-1,2-diphenylethane

There total 3 articles about (1R,2R)-1,2-N,N'-bis(4-methoxyphenylamino)-1,2-diphenylethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E,E)-N1,N2-bis(4-methoxyphenyl)ethane-1,2-diimine (24978-42-5) + phenyllithium (591-51-5) → N,N′-bis(4-methoxyphenyl)-1,2-diphenyl-1,2-ethanediamine + (1R,2R)-1,2-N,N'-bis(4-methoxyphenylamino)-1,2-diphenylethane (170209-09-3) + (1S,2S)-N,N'-Bis-(4-methoxy-phenyl)-1,2-diphenyl-ethane-1,2-diamine

Guidance literature:

With (+)-(S)-1-benzyl-2-(2-methoxyphenoxy)-N,N-dimethylethylamine; In diethyl ether; cyclohexane; toluene; at -78 ℃; for 2h; Title compound not separated from byproducts;

DOI:10.1248/cpb.45.1705

Reference yield:

1,4-Bis(4-methoxyphenyl)-2,3-diphenyl-1,4-diaza-1,3-butadien (32349-49-8) → N,N′-bis(4-methoxyphenyl)-1,2-diphenyl-1,2-ethanediamine + (1R,2R)-1,2-N,N'-bis(4-methoxyphenylamino)-1,2-diphenylethane (170209-09-3)

Guidance literature:

With borane-THF; (2S,3R)-2-amino-3-(t-butyldimethylsiloxy)-1,1-diphenylbutanol; In tetrahydrofuran; for 2h; Product distribution; Ambient temperature; effect of the reagent ratio;

DOI:10.1016/0040-4039(95)01825-3

Reference yield:

[4-(benzylideneamino)phenyl]methanol (783-08-4) → N,N′-bis(4-methoxyphenyl)-1,2-diphenyl-1,2-ethanediamine + (1R,2R)-1,2-N,N'-bis(4-methoxyphenylamino)-1,2-diphenylethane (170209-09-3)

Guidance literature:

With (+)-10-camphorsulfonic acid; copper; zinc; In N,N-dimethyl-formamide; for 30h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1246/cl.1995.609

upstream raw materials:

1,4-Bis(4-methoxyphenyl)-2,3-diphenyl-1,4-diaza-1,3-butadien

[4-(benzylideneamino)phenyl]methanol

(E,E)-N¹,N²-bis(4-methoxyphenyl)ethane-1,2-diimine

phenyllithium

Downstream raw materials:

(4R,5R)-1,3-Bis-(4-methoxy-phenyl)-4,5-diphenyl-imidazolidin-2-one

C₄₃H₄₀N₃O₃P

C₄₃H₄₀N₃O₃P

C₄₂H₃₈N₃O₃P