Cyano-[1,4-diphenyl-azetidin-(2E)-ylidene]-acetic acid methyl ester

Base Information

• Chemical Name: Cyano-[1,4-diphenyl-azetidin-(2E)-ylidene]-acetic acid methyl ester
• CAS No.: 98714-56-8
• Molecular Formula: C₁₉H₁₆N₂O₂
• Molecular Weight: 304.348
• Mol file: 98714-56-8.mol

Synonyms:Cyano-[1,4-diphenyl-azetidin-(2E)-ylidene]-acetic acid methyl ester

Chemical Property of Cyano-[1,4-diphenyl-azetidin-(2E)-ylidene]-acetic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyano-[1,4-diphenyl-azetidin-(2E)-ylidene]-acetic acid methyl ester

There total 2 articles about Cyano-[1,4-diphenyl-azetidin-(2E)-ylidene]-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-3-Chloro-2-cyano-but-2-enoic acid methyl ester (98714-55-7) → Cyano-[1,4-diphenyl-azetidin-(2E)-ylidene]-acetic acid methyl ester (98714-56-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N

2: Et₃N / benzene / 1 h / Heating

With triethylamine; In benzene;

DOI:10.1016/S0040-4020(01)96559-7

Reference yield:

benzylidene phenylamine (538-51-2) + cyano-1 methoxycarbonyl-1 propadiene (93102-12-6) → Cyano-[1,4-diphenyl-azetidin-(2E)-ylidene]-acetic acid methyl ester (98714-56-8)

Guidance literature:

With triethylamine; In benzene; for 1h; Yield given; Heating;

DOI:10.1016/S0040-4020(01)96559-7

Reference yield: 93.0%

Cyano-[1,4-diphenyl-azetidin-(2E)-ylidene]-acetic acid methyl ester (98714-56-8) → 1,4-diphenyl-azetidin-2-one (13474-22-1)

Guidance literature:

With potassium permanganate; magnesium sulfate; In water; acetone; Ambient temperature;

DOI:10.1016/S0040-4020(01)96559-7

upstream raw materials:

benzylidene phenylamine

cyano-1 methoxycarbonyl-1 propadiene

(Z)-3-Chloro-2-cyano-but-2-enoic acid methyl ester

Downstream raw materials:

1,4-diphenyl-azetidin-2-one