ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Base Information

• Chemical Name: ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside
• CAS No.: 1225196-78-0
• Molecular Formula: C₆₂H₆₅NO₁₅S
• Molecular Weight: 1096.26
• Mol file: 1225196-78-0.mol

Synonyms:ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Chemical Property of ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

There total 1 articles about ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-2-deoxy-3-O-(β-D-galactopyranosyl)-2-phthalimido-1-thio-β-D-glucopyranoside (1225196-76-8) + benzaldehyde dimethyl acetal (1125-88-8) → ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside (1225196-78-0)

Guidance literature:

With 10-camphorsufonic acid; In acetonitrile; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2010.01.100

Reference yield: 78.0%

ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside (1225196-78-0) + chloroacetyl chloride (79-04-9) → ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-3-O-chloroacetyl-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside (1225196-80-4)

Guidance literature:

ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside; With di(n-butyl)tin oxide; In toluene; for 3h; Inert atmosphere; Reflux; Molecular sieve;

chloroacetyl chloride; In N,N-dimethyl-formamide; at 0 ℃; for 1h; Inert atmosphere; Molecular sieve;

DOI:10.1016/j.tet.2010.01.100

upstream raw materials:

ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-2-deoxy-3-O-(β-D-galactopyranosyl)-2-phthalimido-1-thio-β-D-glucopyranoside

benzaldehyde dimethyl acetal

Downstream raw materials:

ethyl 6-O-benzyl-4-O-(2,3,4-tri-O-benzyl-β-D-arabinopyranosyl)-3-O-(4,6-O-benzylidene-3-O-chloroacetyl-β-D-galactopyranosyl)-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside