N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine

Base Information

Chemical Name:N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine
CAS No.:185245-95-8
Molecular Formula:C₂₁H₂₂BrNO₆
Molecular Weight:464.313
Hs Code.:

Synonyms:N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine

Suppliers and Price of N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine

There total 8 articles about N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 185245-89-0
6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine

: 64482-27-5
2-bromo-5,6-dimethoxybenzoyl chloride

: 185245-95-8
N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine

Guidance literature:: With sodium hydroxide; In 1,2-dimethoxyethane; Ambient temperature;
DOI:10.1016/S0040-4039(00)73089-9

Reference yield:

: 185245-86-7
1-(2-hydroxyethyl)-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline

: 185245-95-8
N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine

Guidance literature:: Multi-step reaction with 6 steps

1: 100 percent / SOCl₂ / CH₂Cl₂ / 2 h / Heating

2: 72 percent / 28percent NaOMe in MeOH / 1.5 h / Heating

3: 1.) 35percent H₂O₂, 2.) PtO₂ / 1.) CHCl₃, MeOH, RT, 15 h, 2.) CHCl₃, MeOH, 4.5 h

4: tetrahydrofuran / 1 h / Heating

5: 100 percent / H₂ / 10percent Pd/C / methanol / 15 h / 760 Torr

6: 94 percent / 10percent aq. NaOH / 1,2-dimethoxy-ethane / 0.17 h

With platinum(IV) oxide; sodium hydroxide; thionyl chloride; hydrogen; dihydrogen peroxide; sodium methylate; palladium on activated charcoal; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane;
DOI:10.1016/0040-4020(96)00900-3

Reference yield:

: 185245-78-7
7,8-methylenedioxy-1,4,5,9b-tetrahydro-2H-azeto<2,1-a>isoquinoline

: 185245-95-8
N-(6-bromo-2,3-dimethoxybenzoyl)-6-hydroxy-8,9-methylenedioxy-1,2,3,4,5,6-hexahydro-3-benzazocine

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) 35percent H₂O₂, 2.) PtO₂ / 1.) CHCl₃, MeOH, RT, 15 h, 2.) CHCl₃, MeOH, 4.5 h

2: tetrahydrofuran / 1 h / Heating

3: 100 percent / H₂ / 10percent Pd/C / methanol / 15 h / 760 Torr

4: 94 percent / 10percent aq. NaOH / 1,2-dimethoxy-ethane / 0.17 h

With platinum(IV) oxide; sodium hydroxide; hydrogen; dihydrogen peroxide; palladium on activated charcoal; In tetrahydrofuran; methanol; 1,2-dimethoxyethane;
DOI:10.1016/0040-4020(96)00900-3