4,6-dichloro-2-[4-(trifluoromethyl)phenyl]-1,3,5-triazine

Base Information

• Chemical Name: 4,6-dichloro-2-[4-(trifluoromethyl)phenyl]-1,3,5-triazine
• CAS No.: 1207841-73-3
• Molecular Formula: C₁₀H₄Cl₂F₃N₃
• Molecular Weight: 294.063
• Mol file: 1207841-73-3.mol

Synonyms:4,6-dichloro-2-[4-(trifluoromethyl)phenyl]-1,3,5-triazine

Chemical Property of 4,6-dichloro-2-[4-(trifluoromethyl)phenyl]-1,3,5-triazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 4,6-dichloro-2-[4-(trifluoromethyl)phenyl]-1,3,5-triazine

There total 1 articles about 4,6-dichloro-2-[4-(trifluoromethyl)phenyl]-1,3,5-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + p-trifluoromethylphenyl bromide (402-43-7) → 4,6-dichloro-2-[4-(trifluoromethyl)phenyl]-1,3,5-triazine (1207841-73-3)

Guidance literature:

p-trifluoromethylphenyl bromide; With iodine; magnesium; In tetrahydrofuran; at 60 ℃; for 1.5h; Inert atmosphere;

1,3,5-trichloro-2,4,6-triazine; In tetrahydrofuran; at 5 ℃; for 1h; Inert atmosphere;

DOI:10.1039/c5ob02291f

Reference yield: 39.0%

4,6-dichloro-2-[4-(trifluoromethyl)phenyl]-1,3,5-triazine (1207841-73-3) + 2-(trimethylsilyl)phenyl trifluoromethanesulfonate (88284-48-4) → 2,4-bis(2-chlorophenyl)-6-[4-(trifluoromethyl)phenyl]-1,3,5-triazine (1207841-82-4)

Guidance literature:

With potassium fluoride; 18-crown-6 ether; In tetrahydrofuran; at 0 ℃; for 8h; Inert atmosphere;

DOI:10.1246/cl.2009.1132

Reference yield: 39.0%

4,6-dichloro-2-[4-(trifluoromethyl)phenyl]-1,3,5-triazine (1207841-73-3) + 3,5-dihydroxy-4-(phenylmethoxy)benzoic acid methyl ester (91925-82-5) → C50H32F6N6O10

Guidance literature:

With base; In acetonitrile; for 3h; Reflux;

DOI:10.1039/c5ob02291f

upstream raw materials:

1,3,5-trichloro-2,4,6-triazine

p-trifluoromethylphenyl bromide

Downstream raw materials:

2,4-bis(2-chlorophenyl)-6-[4-(trifluoromethyl)phenyl]-1,3,5-triazine