3-(trifluoromethyl)-5,6,7,8-tetrahydro-5,8-dimethyl-[1,2,4]triazolo[4,3-a]pyrazine

Base Information

Chemical Name:3-(trifluoromethyl)-5,6,7,8-tetrahydro-5,8-dimethyl-[1,2,4]triazolo[4,3-a]pyrazine
CAS No.:780754-27-0
Molecular Formula:C₈H₁₁F₃N₄
Molecular Weight:220.197
Hs Code.:
Mol file:780754-27-0.mol

Synonyms:3-(trifluoromethyl)-5,6,7,8-tetrahydro-5,8-dimethyl-[1,2,4]triazolo[4,3-a]pyrazine

Suppliers and Price of 3-(trifluoromethyl)-5,6,7,8-tetrahydro-5,8-dimethyl-[1,2,4]triazolo[4,3-a]pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3-(trifluoromethyl)-5,6,7,8-tetrahydro-5,8-dimethyl-[1,2,4]triazolo[4,3-a]pyrazine

Chemical Property:

Vapor Pressure:0.005mmHg at 25°C
Refractive Index:1.58
Boiling Point:275.7°C at 760 mmHg
Flash Point:120.6°C
PSA：42.74000
Density:1.55g/cm³
LogP:1.85090

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(trifluoromethyl)-5,6,7,8-tetrahydro-5,8-dimethyl-[1,2,4]triazolo[4,3-a]pyrazine

There total 1 articles about 3-(trifluoromethyl)-5,6,7,8-tetrahydro-5,8-dimethyl-[1,2,4]triazolo[4,3-a]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1013656-73-9
5,8-dimethyl-3-(trifluoromethyl)-1,2,4-triazolo[4,3a]pyrazine

: 780754-27-0
5,8-dimethyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; at 20 ℃; for 18h;
DOI:10.1021/jm070330v

Reference yield:

: 780754-27-0
5,8-dimethyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine

: 486460-00-8,922178-94-7
(3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid

: 1013656-78-4
tert-butyl [(1R)-3-[(5R,8R)-dimethyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate

: 1013656-79-5
tert-butyl [(1R)-3-[(5S,8S)-dimethyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate

Guidance literature:: With 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 18h;
DOI:10.1021/jm070330v