18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol

Base Information

Chemical Name:18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol
CAS No.:812653-13-7
Molecular Formula:C₃₅H₅₃NO₆S
Molecular Weight:615.875
Hs Code.:

18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1<i>H</i>-indol-3-yl]-octadecan-1-ol

Synonyms:18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol

Suppliers and Price of 18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol

There total 15 articles about 18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 3-(18-benzyloxy-octadec-1-enyl)-5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indole

: 812653-13-7
18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; under 760 Torr;
DOI:10.1021/jm0493616

Reference yield:

: 59101-27-8
15-bromopentadecane-1-ol

: 812653-13-7
18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol

Guidance literature:: Multi-step reaction with 8 steps

1.1: PCC / CH₂Cl₂ / 20 °C

2.1: NaH / tetrahydrofuran

2.2: tetrahydrofuran / 0 - 20 °C

3.1: H₂ / Pd/C / ethanol / 20 °C

4.1: LiAlH₄ / tetrahydrofuran / 0 - 20 °C

5.1: NaH / tetrahydrofuran / Heating

6.1: acetonitrile / Heating

7.1: n-BuLi / tetrahydrofuran; hexane / 0 °C

7.2: potassium tert-butoxide / tetrahydrofuran; hexane / 0 °C

7.3: 71 percent / tetrahydrofuran; hexane / -78 - 0 °C

8.1: 90 percent / H₂ / Pd/C / ethanol / 20 °C / 760 Torr

With lithium aluminium tetrahydride; n-butyllithium; hydrogen; sodium hydride; pyridinium chlorochromate; palladium on activated charcoal; In tetrahydrofuran; ethanol; hexane; dichloromethane; acetonitrile; 7.3: Wittig reaction;
DOI:10.1021/jm0493616

Reference yield:

: 88210-96-2
5,6-dimethoxyindole-2-carboxylic acid

: 812653-13-7
18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol

Guidance literature:: Multi-step reaction with 5 steps

1.1: 61 percent / Cu; quinoline / Heating

2.1: 86 percent / phosphoryl chloride / 0 - 40 °C

3.1: NaOH / CH₂Cl₂ / 20 °C

3.2: 26 percent / CH₂Cl₂ / 20 °C

4.1: n-BuLi / tetrahydrofuran; hexane / 0 °C

4.2: potassium tert-butoxide / tetrahydrofuran; hexane / 0 °C

4.3: 71 percent / tetrahydrofuran; hexane / -78 - 0 °C

5.1: 90 percent / H₂ / Pd/C / ethanol / 20 °C / 760 Torr

With quinoline; sodium hydroxide; n-butyllithium; hydrogen; copper; trichlorophosphate; palladium on activated charcoal; In tetrahydrofuran; ethanol; hexane; dichloromethane; 2.1: Vilsmeier formylation / 4.3: Wittig reaction;
DOI:10.1021/jm0493616