17-Benzyl-7,9,20-trimethyl-2,14-dioxo-3,13-diaza-17-azonia-tricyclo[13.3.1.1^6,10]icosa-1⁽¹⁸⁾,6,8,10⁽²⁰⁾,15⁽¹⁹⁾,16-hexaene; bromide

Base Information

• Chemical Name: 17-Benzyl-7,9,20-trimethyl-2,14-dioxo-3,13-diaza-17-azonia-tricyclo[13.3.1.1^6,10]icosa-1⁽¹⁸⁾,6,8,10⁽²⁰⁾,15⁽¹⁹⁾,16-hexaene; bromide
• CAS No.: 75340-04-4
• Molecular Formula: Br*C₂₇H₃₀N₃O₂
• Molecular Weight: 508.458
• Mol file: 75340-04-4.mol

Synonyms:17-Benzyl-7,9,20-trimethyl-2,14-dioxo-3,13-diaza-17-azonia-tricyclo[13.3.1.1^6,10]icosa-1⁽¹⁸⁾,6,8,10⁽²⁰⁾,15⁽¹⁹⁾,16-hexaene; bromide

Chemical Property of 17-Benzyl-7,9,20-trimethyl-2,14-dioxo-3,13-diaza-17-azonia-tricyclo[13.3.1.1^6,10]icosa-1⁽¹⁸⁾,6,8,10⁽²⁰⁾,15⁽¹⁹⁾,16-hexaene; bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 17-Benzyl-7,9,20-trimethyl-2,14-dioxo-3,13-diaza-17-azonia-tricyclo[13.3.1.1^6,10]icosa-1⁽¹⁸⁾,6,8,10⁽²⁰⁾,15⁽¹⁹⁾,16-hexaene; bromide

There total 3 articles about 17-Benzyl-7,9,20-trimethyl-2,14-dioxo-3,13-diaza-17-azonia-tricyclo[13.3.1.1^6,10]icosa-1⁽¹⁸⁾,6,8,10⁽²⁰⁾,15⁽¹⁹⁾,16-hexaene; bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

benzyl bromide (100-39-0) + 7,9,20-Trimethyl-3,13,17-triaza-tricyclo[13.3.1.16,10]icosa-1(18),6,8,10(20),15(19),16-hexaene-2,14-dione (90433-41-3) → 17-Benzyl-7,9,20-trimethyl-2,14-dioxo-3,13-diaza-17-azonia-tricyclo[13.3.1.16,10]icosa-1(18),6,8,10(20),15(19),16-hexaene; bromide (75340-04-4)

Guidance literature:

at 80 ℃; for 1h;

DOI:10.1021/ja00325a020

Reference yield:

3,5-Pyridinedicarboxylic acid (499-81-0) → 17-Benzyl-7,9,20-trimethyl-2,14-dioxo-3,13-diaza-17-azonia-tricyclo[13.3.1.16,10]icosa-1(18),6,8,10(20),15(19),16-hexaene; bromide (75340-04-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / tionyl chloride / Heating

2: 10 percent / triethylamine / toluene / 50 h / Ambient temperature

3: 70 percent / 1 h / 80 °C

With thionyl chloride; triethylamine; In toluene;

DOI:10.1021/ja00325a020

Reference yield:

pyridine-3,5-dicarbonyl dichloride (15074-61-0) → 17-Benzyl-7,9,20-trimethyl-2,14-dioxo-3,13-diaza-17-azonia-tricyclo[13.3.1.16,10]icosa-1(18),6,8,10(20),15(19),16-hexaene; bromide (75340-04-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 10 percent / triethylamine / toluene / 50 h / Ambient temperature

2: 70 percent / 1 h / 80 °C

With triethylamine; In toluene;

DOI:10.1021/ja00325a020

upstream raw materials:

benzyl bromide

7,9,20-Trimethyl-3,13,17-triaza-tricyclo[13.3.1.1^6,10]icosa-1⁽¹⁸⁾,6,8,10⁽²⁰⁾,15⁽¹⁹⁾,16-hexaene-2,14-dione

3,5-Pyridinedicarboxylic acid

pyridine-3,5-dicarbonyl dichloride

Downstream raw materials:

17-Benzyl-7,9,20-trimethyl-3,13,17-triaza-tricyclo[13.3.1.1^6,10]icosa-1⁽¹⁸⁾,6,8,10⁽²⁰⁾,15-pentaene-2,14-dione