Technology Process of 8-benzyloxy-2,3-dibromo-4,4-dimethoxy-6-methylnaphthalene
There total 8 articles about 8-benzyloxy-2,3-dibromo-4,4-dimethoxy-6-methylnaphthalene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N,N,N',N'-tetramethyl-1,8-diaminonaphthalene;
In
dichloromethane;
at 0 - 20 ℃;
for 1.5h;
Inert atmosphere;
Molecular sieve;
DOI:10.1016/j.tet.2011.05.117
- Guidance literature:
-
Multi-step reaction with 3 steps
1: pyridinium hydrobromide perbromide / dichloromethane / 0.83 h / 0 °C / Inert atmosphere
2: sodium dithionite; water / diethyl ether; dichloromethane / Inert atmosphere
3: N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 1.5 h / 0 - 20 °C / Inert atmosphere; Molecular sieve
With
sodium dithionite; pyridinium hydrobromide perbromide; water; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene;
In
diethyl ether; dichloromethane;
DOI:10.1016/j.tet.2011.05.117
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: silver(l) oxide / chloroform / 72 h / 20 °C / Inert atmosphere; Darkness
2.1: bromine / chloroform / 1 h / 0 °C / Inert atmosphere
2.2: 0.25 h / 0 °C / Inert atmosphere
3.1: pyridinium hydrobromide perbromide / dichloromethane / 0.83 h / 0 °C / Inert atmosphere
4.1: sodium dithionite; water / diethyl ether; dichloromethane / Inert atmosphere
5.1: N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 1.5 h / 0 - 20 °C / Inert atmosphere; Molecular sieve
With
sodium dithionite; pyridinium hydrobromide perbromide; water; bromine; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; silver(l) oxide;
In
diethyl ether; dichloromethane; chloroform;
DOI:10.1016/j.tet.2011.05.117
