P-[2-(diphenylphosphino)phenyl]-N,N-diisopropyl-P-phenylphosphinic amide

Base Information

• Chemical Name: P-[2-(diphenylphosphino)phenyl]-N,N-diisopropyl-P-phenylphosphinic amide
• CAS No.: 1198339-44-4
• Molecular Formula: C₃₀H₃₃NOP₂
• Molecular Weight: 485.546
• Mol file: 1198339-44-4.mol

Synonyms:P-[2-(diphenylphosphino)phenyl]-N,N-diisopropyl-P-phenylphosphinic amide

Chemical Property of P-[2-(diphenylphosphino)phenyl]-N,N-diisopropyl-P-phenylphosphinic amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of P-[2-(diphenylphosphino)phenyl]-N,N-diisopropyl-P-phenylphosphinic amide

There total 3 articles about P-[2-(diphenylphosphino)phenyl]-N,N-diisopropyl-P-phenylphosphinic amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N,N-Di-isopropyl-P,P-diphenylphosphinic amide (131173-04-1) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → P-[2-(diphenylphosphino)phenyl]-N,N-diisopropyl-P-phenylphosphinic amide (1198339-44-4)

Guidance literature:

N,N-Di-isopropyl-P,P-diphenylphosphinic amide; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; toluene; at -78 ℃; for 1h; Inert atmosphere; Schlenk technique;

chloro-diphenylphosphine; at 20 ℃; for 2h; Reagent/catalyst; Solvent; Inert atmosphere; Schlenk technique;

DOI:10.1039/c4dt01789g

Reference yield:

chloro-diphenylphosphine (1079-66-9,74391-44-9) → P-[2-(diphenylphosphino)phenyl]-N,N-diisopropyl-P-phenylphosphinic amide (1198339-44-4)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine

2: N,N,N,N,-tetramethylethylenediamine; n-butyllithium

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; triethylamine;

DOI:10.1021/acscatal.5b01490

Reference yield:

diisopropylamine (108-18-9) → P-[2-(diphenylphosphino)phenyl]-N,N-diisopropyl-P-phenylphosphinic amide (1198339-44-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: dihydrogen peroxide / Inert atmosphere

2.1: N,N,N,N,-tetramethylethylenediamine; n-butyllithium / Inert atmosphere

2.2: Inert atmosphere

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; dihydrogen peroxide;

DOI:10.1039/c8dt01018h

upstream raw materials:

N,N-Di-isopropyl-P,P-diphenylphosphinic amide

chloro-diphenylphosphine

diisopropylamine