C₃₄H₄₄N₄O₉

Base Information

• Chemical Name: C₃₄H₄₄N₄O₉
• CAS No.: 1326757-09-8
• Molecular Formula: C₃₄H₄₄N₄O₉
• Molecular Weight: 652.745
• Mol file: 1326757-09-8.mol

Synonyms:C₃₄H₄₄N₄O₉

Chemical Property of C₃₄H₄₄N₄O₉

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₃₄H₄₄N₄O₉

There total 4 articles about C₃₄H₄₄N₄O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C42H50N4O11 (1326757-08-7) → C34H44N4O9 (1326757-09-8)

Guidance literature:

With palladium on carbon; hydrogen; In methanol; at 20 ℃; for 12h;

DOI:10.1002/chem.201100715

Reference yield:

di-tert-butyl 4-(((benzyloxy)carbonyl)amino)-4-(3-(tert-butoxy)-3-oxopropyl)heptanedioate → C34H44N4O9 (1326757-09-8)

Guidance literature:

Multi-step reaction with 3 steps

1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 0 - 20 °C

3: palladium on carbon; hydrogen / methanol / 12 h / 20 °C

With palladium on carbon; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/chem.201100715

Reference yield:

4-amino-4-(2-tert-butoxycarbonylethyl)heptanedioic acid di-tertbutyl ester (136586-99-7) → C34H44N4O9 (1326757-09-8)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium carbonate / 1,4-dioxane; water / 4 h / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 0 - 20 °C

4: palladium on carbon; hydrogen / methanol / 12 h / 20 °C

With palladium on carbon; hydrogen; sodium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; In 1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1002/chem.201100715

upstream raw materials:

di-tert-butyl 4-benzyloxycarbonylamino-4-[2-(tert-butoxycarbonyl)ethyl]-heptanedioate

C₄₂H₅₀N₄O₁₁

4-amino-4-(2-tert-butoxycarbonylethyl)heptanedioic acid di-tertbutyl ester

Downstream raw materials:

C₄₄H₅₃N₅O₁₂