4-[4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine

Base Information

Chemical Name:4-[4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine
CAS No.:1609259-56-4
Molecular Formula:C₂₆H₃₂N₄O₂Si
Molecular Weight:460.651
Hs Code.:

Synonyms:4-[4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine

Suppliers and Price of 4-[4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine

There total 6 articles about 4-[4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1609259-25-7
4-chloro-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine

: 1609259-55-3
4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenol

: 1609259-56-4
4-[4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine

Guidance literature:: With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In 1,4-dioxane; at 120 ℃; for 2h;

Reference yield:

: 2-(2-methyl-4-methoxyphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

: 1609259-56-4
4-[4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium phosphate / water; 1,4-dioxane; ethyl acetate; Petroleum ether / 4 h / Reflux

2: boron tribromide / dichloromethane / 16 h / -70 - 20 °C / pH 8

3: 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate; caesium carbonate / 1,4-dioxane / 2 h / 120 °C

With potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; palladium diacetate; boron tribromide; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In 1,4-dioxane; dichloromethane; water; ethyl acetate; Petroleum ether;

Reference yield:

: 157335-97-2
4,6-dimethyl-5-bromopyrimidine

: 1609259-56-4
4-[4-(4,6-dimethylpyrimidin-5-yl)-3-methylphenoxy]-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[3,2-c]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium phosphate / water; 1,4-dioxane; ethyl acetate; Petroleum ether / 4 h / Reflux

2: boron tribromide / dichloromethane / 16 h / -70 - 20 °C / pH 8

3: 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate; caesium carbonate / 1,4-dioxane / 2 h / 120 °C

With potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; palladium diacetate; boron tribromide; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In 1,4-dioxane; dichloromethane; water; ethyl acetate; Petroleum ether;