C₂₇H₂₁F₅N₂O

Base Information

Chemical Name:C₂₇H₂₁F₅N₂O
CAS No.:1443429-57-9
Molecular Formula:C₂₇H₂₁F₅N₂O
Molecular Weight:484.469
Hs Code.:

C<sub>27</sub>H<sub>21</sub>F<sub>5</sub>N<sub>2</sub>O

Synonyms:C₂₇H₂₁F₅N₂O

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Chemical Property of C₂₇H₂₁F₅N₂O

Chemical Property:

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Technology Process of C₂₇H₂₁F₅N₂O

There total 5 articles about C₂₇H₂₁F₅N₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1765-93-1
4-fluoroboronic acid

: 1443429-57-9
C₂₇H₂₁F₅N₂O

Guidance literature:: Multi-step reaction with 4 steps

1.1: copper diacetate; pyridine / dichloromethane / 16 h / 20 °C / Molecular sieve

2.1: dimethyl sulfoxide; oxalyl dichloride / dichloromethane / -78 °C / Inert atmosphere

2.2: -78 - 20 °C

3.1: potassium carbonate / methanol / 0.5 h / 20 °C / Inert atmosphere

4.1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 0.33 h / 120 °C / Inert atmosphere; Microwave irradiation

With pyridine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; oxalyl dichloride; copper diacetate; potassium carbonate; dimethyl sulfoxide; triethylamine; In methanol; dichloromethane;

Reference yield:

: 1296224-53-7
C₁₂H₁₆FNO

: 1443429-57-9
C₂₇H₂₁F₅N₂O

Guidance literature:: Multi-step reaction with 3 steps

1.1: dimethyl sulfoxide; oxalyl dichloride / dichloromethane / -78 °C / Inert atmosphere

1.2: -78 - 20 °C

2.1: potassium carbonate / methanol / 0.5 h / 20 °C / Inert atmosphere

3.1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 0.33 h / 120 °C / Inert atmosphere; Microwave irradiation

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; oxalyl dichloride; potassium carbonate; dimethyl sulfoxide; triethylamine; In methanol; dichloromethane;

Reference yield:

: 851265-38-8
4-fluorophenyl-4-piperidinyl methanone

: 1443429-57-9
C₂₇H₂₁F₅N₂O

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / methanol / 0.5 h / 20 °C / Inert atmosphere

2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 0.33 h / 120 °C / Inert atmosphere; Microwave irradiation

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium carbonate; triethylamine; In methanol;