N-ethyl-N-benzyloxycarbonylaniline

Base Information

• Chemical Name: N-ethyl-N-benzyloxycarbonylaniline
• CAS No.: 101293-20-3
• Molecular Formula: C₁₆H₁₇NO₂
• Molecular Weight: 255.316
• Mol file: 101293-20-3.mol

Synonyms:N-ethyl-N-benzyloxycarbonylaniline

Chemical Property of N-ethyl-N-benzyloxycarbonylaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of N-ethyl-N-benzyloxycarbonylaniline

There total 4 articles about N-ethyl-N-benzyloxycarbonylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.3%

DBC (3459-92-5) + N-ethyl-N-phenylamine (103-69-5) → N-ethyl-N-benzyloxycarbonylaniline (101293-20-3)

Guidance literature:

N-ethyl-N-phenylamine; With n-butyllithium; In tert-butyl methyl ether; cyclohexane; at 5 ℃; for 0.0125h; under 7500.75 Torr;

DBC; In tert-butyl methyl ether; cyclohexane; at 0 ℃; for 0.0125h;

Reference yield: 78.0%

carbon dioxide (124-38-9,18923-20-1) + benzyl chloride (100-44-7) + N-ethyl-N-phenylamine (103-69-5) → N-ethyl-N-benzyloxycarbonylaniline (101293-20-3)

Guidance literature:

carbon dioxide; N-ethyl-N-phenylamine; With tetra-(n-butyl)ammonium iodide; caesium carbonate; In N,N-dimethyl-formamide; at 23 ℃; for 1h;

benzyl chloride; In N,N-dimethyl-formamide; at 23 ℃; for 22h;

DOI:10.1016/S0040-4020(02)00286-7

Reference yield: 78.0%

N-ethyl-N-phenylamine (103-69-5) + benzyl chloroformate (501-53-1,94274-21-2) → N-ethyl-N-benzyloxycarbonylaniline (101293-20-3)

Guidance literature:

With potassium carbonate; In toluene; at 80 ℃; for 6h; Inert atmosphere;

DOI:10.1021/jacs.7b13087

upstream raw materials:

ethyl-phenyl-carbamic acid ethyl ester

benzyl alcohol

carbon dioxide

benzyl chloride