6-(4-chloro-3-methylphenyl)-3-(hydrazinocarbonylmethoxy)pyridazine

Base Information

• Chemical Name: 6-(4-chloro-3-methylphenyl)-3-(hydrazinocarbonylmethoxy)pyridazine
• CAS No.: 855784-94-0
• Molecular Formula: C₁₃H₁₃ClN₄O₂
• Molecular Weight: 292.725
• Mol file: 855784-94-0.mol

Synonyms:6-(4-chloro-3-methylphenyl)-3-(hydrazinocarbonylmethoxy)pyridazine

Chemical Property of 6-(4-chloro-3-methylphenyl)-3-(hydrazinocarbonylmethoxy)pyridazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-(4-chloro-3-methylphenyl)-3-(hydrazinocarbonylmethoxy)pyridazine

There total 3 articles about 6-(4-chloro-3-methylphenyl)-3-(hydrazinocarbonylmethoxy)pyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

6-(4-chloro-3-methylphenyl)-3-(ethoxycarbonylmethoxy)pyridazine (855784-93-9) → 6-(4-chloro-3-methylphenyl)-3-(hydrazinocarbonylmethoxy)pyridazine (855784-94-0)

Guidance literature:

With hydrazine hydrate; In ethanol; for 4h; Heating;

DOI:10.1139/v05-045

Reference yield:

6-(4-chloro-3-methylphenyl)-4-(3,5-dimethylpyrazol-1-yl)-2,3,4,5-tetrahydropyridazin-3-one → 6-(4-chloro-3-methylphenyl)-3-(hydrazinocarbonylmethoxy)pyridazine (855784-94-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / potassium carbonate / dioxane / 24 h / Heating

2: 82 percent / hydrazine hydrate / ethanol / 4 h / Heating

With potassium carbonate; hydrazine hydrate; In 1,4-dioxane; ethanol;

DOI:10.1139/v05-045

Reference yield:

C11H9ClN2O → 6-(4-chloro-3-methylphenyl)-3-(hydrazinocarbonylmethoxy)pyridazine (855784-94-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone

2: hydrazine hydrate / ethanol / 12 h / Reflux

With potassium carbonate; hydrazine hydrate; In ethanol; acetone;

DOI:10.1002/jhet.3662

upstream raw materials:

6-(4-chloro-3-methylphenyl)-3-(ethoxycarbonylmethoxy)pyridazine