(E)-4-(2-methoxyimino-2-[2-(o-tolyloxymethyl)phenyl]acetamido)hexanoic acid

Base Information

• Chemical Name: (E)-4-(2-methoxyimino-2-[2-(o-tolyloxymethyl)phenyl]acetamido)hexanoic acid
• CAS No.: 1007364-31-9
• Molecular Formula: C₂₃H₂₈N₂O₅
• Molecular Weight: 412.486
• Mol file: 1007364-31-9.mol

Synonyms:(E)-4-(2-methoxyimino-2-[2-(o-tolyloxymethyl)phenyl]acetamido)hexanoic acid

Chemical Property of (E)-4-(2-methoxyimino-2-[2-(o-tolyloxymethyl)phenyl]acetamido)hexanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of (E)-4-(2-methoxyimino-2-[2-(o-tolyloxymethyl)phenyl]acetamido)hexanoic acid

There total 1 articles about (E)-4-(2-methoxyimino-2-[2-(o-tolyloxymethyl)phenyl]acetamido)hexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

(E)-2-methoxyimino-2-{[2-(2-tolyl)oxymethyl]phenyl}acetic acid (1007364-30-8) + 6-aminohexanoic acid (60-32-2,93208-38-9) → (E)-4-(2-methoxyimino-2-[2-(o-tolyloxymethyl)phenyl]acetamido)hexanoic acid (1007364-31-9)

Guidance literature:

(E)-2-methoxyimino-2-{[2-(2-tolyl)oxymethyl]phenyl}acetic acid; With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 4 - 20 ℃; for 24h; Inert atmosphere;

6-aminohexanoic acid; With sodium hydrogencarbonate; In tetrahydrofuran; water; at 20 ℃; for 40h;

DOI:10.1021/jf073039x

Reference yield:

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + (E)-4-(2-methoxyimino-2-[2-(o-tolyloxymethyl)phenyl]acetamido)hexanoic acid (1007364-31-9) → C27H31N3O7

Guidance literature:

With dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1021/jf073039x

upstream raw materials:

(E)-2-methoxyimino-2-{[2-(2-tolyl)oxymethyl]phenyl}acetic acid

6-aminohexanoic acid