6-(6-Chloro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

Base Information

Chemical Name:6-(6-Chloro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole
CAS No.:1476848-16-4
Molecular Formula:C₂₃H₁₅ClN₄O₃S₂
Molecular Weight:494.982
Hs Code.:

Synonyms:6-(6-Chloro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

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Chemical Property of 6-(6-Chloro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

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Technology Process of 6-(6-Chloro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

There total 6 articles about 6-(6-Chloro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 23780-13-4
(2-phenylthiazol-4-yl)methanol

: 1476848-25-5
6-chloro-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzofuran-4-ol

: 1476848-16-4
6-(6-Chloro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: With tributylphosphine; In tetrahydrofuran; diethyl ether;

Reference yield:

: 1476848-21-1
1-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-bromoethanone

: 1476848-16-4
6-(6-Chloro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: Multi-step reaction with 4 steps

2: hydrogenchloride; sodium methylate / methanol

3: boron trichloride; sodium hydrogencarbonate / water

4: tributylphosphine / tetrahydrofuran; diethyl ether

With hydrogenchloride; tributylphosphine; sodium methylate; boron trichloride; sodium hydrogencarbonate; In tetrahydrofuran; methanol; diethyl ether; water;

Reference yield:

: 1476848-23-3
6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-bromoimidazo[2,1-b][1,3,4]thiadiazole

: 1476848-16-4
6-(6-Chloro-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride; sodium methylate / methanol

2: boron trichloride; sodium hydrogencarbonate / water

3: tributylphosphine / tetrahydrofuran; diethyl ether

With hydrogenchloride; tributylphosphine; sodium methylate; boron trichloride; sodium hydrogencarbonate; In tetrahydrofuran; methanol; diethyl ether; water;