6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

Base Information

Chemical Name:6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole
CAS No.:1476848-24-4
Molecular Formula:C₂₀H₁₄ClN₃O₃S
Molecular Weight:411.868
Hs Code.:

Synonyms:6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

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Chemical Property of 6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

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Technology Process of 6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

There total 10 articles about 6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 67-56-1
methanol

: 1476848-23-3
6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-bromoimidazo[2,1-b][1,3,4]thiadiazole

: 1476848-24-4
6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: With sodium methylate; In dichloromethane; at 20 ℃; for 1.25h;

Reference yield: 81.0%

: 1476848-23-3
6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-bromoimidazo[2,1-b][1,3,4]thiadiazole

: 1476848-24-4
6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: With hydrogenchloride; sodium methylate; In methanol;

Reference yield:

: 1476848-21-1
1-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-bromoethanone

: 1476848-24-4
6-(4-(benzyloxy)-6-chlorobenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: Multi-step reaction with 2 steps

2: hydrogenchloride; sodium methylate / methanol

With hydrogenchloride; sodium methylate; In methanol;